MỐI LIÊN QUAN CỦA KHOẢNG TRỐNG ANION ƯỚC TÍNH VỚI TỈ LỆ TỬ VONG Ở BỆNH NHÂN NHIỄM KHUẨN NẶNG (SEPSIS) TẠI TRUNG TÂM CẤP CỨU A9 – BỆNH VIỆN BẠCH MAI

Abstract

Objectives: To describe the characteristics and evaluate the relationship between estimated anion gap (AG) and 30-day mortality rate in patients with sepsis at A9 Emergency Center - Bach Mai Hospital. Methods: A prospective descriptive study of 206 patients with sepsis from October 2024 to March 2025. Selection criteria included: Patients ≥ 16 years old, diagnosed with sepsis according to the Sepsis-3 2016 criteria of the Surviving Sepsis Campaign. Results: Males accounted for 64.1%, with a mean age of 64.1 ± 15.83 years. Among the 206 patients, 97 cases were diagnosed with septic shock, representing 47%. The estimated AG value at hospital admission was 18.1 ± 7.0, with the 30-day survivor group showing 15.56 ± 0.5, and the mortality group showing 21.78 ± 0.8; the difference was statistically significant with p < 0.05. The ROC curve of estimated AG showed value in predicting 30-day mortality with AUC: 0.75, cutoff point 17.85, sensitivity 76.2%, and specificity 67.2%. Conclusions: Estimated AG can be used as a surrogate parameter to predict mortality risk in severe sepsis when other variables are not immediately available.