PREVALENCE OF FAMILY HISTORY OF DIABETES THROUGH ANALYSIS OF THE FAMILY HEALTH HISTORY OF PATIENTS WITH TYPE 2 DIABETES
Main Article Content
Abstract
Background: In the current era of genetic medicine, scientists have researched and proven that in addition to environmental factors, genetic factors also contribute to the rapid increase in the incidence of diabetes. Therefore, learning about the family history of diabetes through building and analyzing the family health history of type 2 diabetes patients is an important step as a genetic assessment tool, a strong, independent, and easily measured predictor of diabetes. Objective: To determine the proportion of patients with type 2 diabetes who have a history of first-degree relatives and second-degree relatives with diabetes. Patients and methods: Cross-sectional study. We selected all patients diagnosed with type 2 diabetes who came for examination at the Endocrinology clinic of Ho Chi Minh City University of Medicine and Pharmacy Hospital from April 2023 to August 2023. Results: Among 236 type 2 diabetes patients participating in the study, the proportion of patients with a positive family health history for diabetes was 48,3%. The proportion of type 2 diabetes patients with a history of first-degree relatives with diabetes is 92,1% and of type 2 diabetes patients with a history of second-degree relatives with diabetes is 34,2%. Patients with a sibling with diabetes account for half of first-degree relatives (55,2%). Patients whose mothers have diabetes account for a higher rate than their fathers with diabetes (20% versus 9,5%), and patients with both parents with diabetes are 4,8%. The rate of patients with children with diabetes was recorded at 7,6%, patients with both parents and brothers and sisters with diabetes account for a low rate of 2,9%. Conclusion: The proportion of patients with type 2 diabetes with a positive family health history of diabetes is very common. Patients with first-degree relatives with diabetes account for a high proportion, especially siblings. The mother has a significant genetic impact on patients with type 2 diabetes. In clinical practice, it is necessary to explore information about the family history of diabetes.
Article Details
Keywords
Family health history, type 2 diabetes mellitus, family history of diabetes
References
2. Centre for Disease Control and Prevention. Family Health History: The Basics. Updated May 25, 2020. Accessed November 22, 2022. https://www.cdc.gov/genomics/famhistory/famhist_basics.htm
3. Bennett RL. Family Health History: The First Genetic Test in Precision Medicine. Med Clin North Am. 2019/11// 2019; 103(6):957-966. doi:10. 1016/j.mcna.2019.06.002
4. Bener A, Yousafzai MT, Al-Hamaq AO, Mohammad AG, Defronzo RA. Parental transmission of type 2 diabetes mellitus in a highly endogamous population. World J Diabetes. Apr 15 2013;4(2):40-46. doi:10.4239/wjd.v4.i2.40
5. A G, S G, R U. Study on the impact of family history of diabetes among type 2 diabetes mellitus patients in an urban area of Kancheepuram district, Tamil Nadu. International Journal Of Community Medicine And Public Health. 2017; 4(11):4151-4156.
6. Katulanda P, Ranasinghe P, Jayawardena R, Sheriff R, Matthews DR. The influence of family history of diabetes on disease prevalence and associated metabolic risk factors among Sri Lankan adults. Diabet Med. Mar 2015;32(3):314-323.
7. Liao PJ, Ting MK, Kuo CF, Ding YH, Lin CM, Hsu KH. Kinship analysis of type 2 diabetes mellitus familial aggregation in Taiwan. Biomed J. Aug 2023;46(4): 100549. doi: 10.1016/j.bj.2022. 07.003
8. Zhang Y, Chen H, Lu H, et al. Prevalence and risk of diabetes based on family history in the Shanghai High-Risk Diabetic Screen (SHiDS) study. Diabet Med. Dec 2016;33(12):1705-1711. doi:10.1111/dme.13013