ĐẶC ĐIỂM MÔ BỆNH HỌC CỦA UNG THƯ BIỂU MÔ TUYẾN GIÁP BIỆT HÓA TẠI BỆNH VIỆN NỘI TIẾT TRUNG ƯƠNG NĂM 2023

Abstract

Objective: Describe the histopathological characteristics of differentiated thyroid carcinoma according to the WHO 2022 classification at the National Endocrine Hospital. Patients and methods: Cross-sectional descriptive study on 506 patients operated on and diagnosed with differentiated thyroid carcinoma at the National Endocrine Hospital from February 1, 2023 to November 30, 2023. Results: female/male ratio is 5.9/1. The average age of disease is 46.0 ± 12.3 years. The majority of tumors were only detected in one lobe of the thyroid gland (72.3%) and the tumors were mainly unifocal (92.8%). Common tumor size is 0.1-0.5 cm in 46.1%. Differentiated thyroid carcinoma includes papillary carcinoma, invasive encapsulated follicular variant of papillary carcinoma, follicular carcinoma and oncocytic carcinoma with rates of 96.9%, 0.8%, 2.1% and 0.2% respectively. In papillary carcinoma, classic subtype accounts for the majority with 86.7%, the second is infiltrative follicular subtype with 7.6%. Conclusion: Through the study of 621 thyroid tumors in 506 patients, we found that the majority of tumors are less than 1cm in size (84.1%), often detected on 1 thyroid lobe (72.3%), and unifocal tumors are the majority (92.8%). Papillary carcinoma is the most common differentiated thyroid carcinoma with a rate of 96.9%, of which the main type is classic subtype with 86.7%.