VALIDATION OF THE MODIFIED CENTOR SCORES TO DIAGNOSIS OF GROUP A STREPTOCOCCAL ACUTE PHARYNGITIS

Thị Diễm Nguyễn , Phan Chung Thủy Trần

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Abstract

Objectives: Evaluate the modified Centor scores to diagnosis of group A streptococcal acute pharyngitis. Methods: Cross-sectional prospective study. Results: 82 acute pharyngitis patients, the mean age was 16.82 ± 15.03 (range 3-62 years); the rate of patients contributed by modified Centor scores were 1pt 11.0%, 2pts 46.3%, 3pts 24.4%, 4pts 17.1% and 5pts 1.2%. The positive test and culture was 22.0%. With the 2pts cutoff, there were the best diagnostic values: the sensitivity was 100%, specificity was 73%; PPV was 51%, and NPV was 100%. The rate of fault positive was 27%, fault negative was 0%. The area under the ROC curve (AUC) was 0.71 (SE=0.06, p=0.001, 95% CI 0.59-0.82). Conclusions: The modified Centor scores were clinical scores helpful to diagnosis of group A streptococcal acute pharyngitis.

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References

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