ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG VÀ NGUYÊN NHÂN SUY GAN CẤP Ở BỆNH NHÂN ĐƯỢC ĐIỀU TRỊ THAY HUYẾT TƯƠNG TẠI KHOA HỒI SỨC TÍCH CỰC - BỆNH VIỆN HỮU NGHỊ

Abstract

Objective: Describe the clinical and paraclinical characteristics and causes of acute liver failure in patients receiving plasma exchange therapy in the Critical Care Department. Subjects: Patients with acute liver failure treated at the Critical care department - Huu Nghi Hospital; from January 2019 to October 2023. Research methods: prospective, descriptive. Results: mean age 76.0; male ratio 81.5%; Patients have 55.6% multi-organ failure; 33.3% thrombocytopenia; 14.9% had severe hemodynamic disorders; increased liver enzymes, average total bilirubin 273.4 ± 57.2 mmol/l, 51.9% liver-kidney syndrome. Causes of acute liver failure: 51% due to poisoning, 26% due to viral hepatitis. Conclusion: Elderly patients, mainly male, with hepatic coma from grade 2 or higher, most have multi-organ failure, elevated liver enzymes and bilirubin, and blood clotting disorders. The main cause is acute poisoning.