ĐÁNH GIÁ HIỆU QUẢ THAY HUYẾT TƯƠNG TRONG ĐIỀU TRỊ SUY GAN CẤP TẠI KHOA HỒI SỨC BỆNH VIỆN HỮU NGHỊ

Abstract

Objective: Evaluate the effectiveness and some common complications of plasma exchange in the treatment of acute liver failure at the Critical Care Department. Subjects: Patients with acute liver failure treated at the Critical care department - Huu Nghi Hospital; from January 2019 to October 2023. Research methods: prospective, intervention. Results: average number of plasma exchanges 3.2 ± 1.7 times; After plasma exchange treatment, the patient's liver coma, multiple organ failure, coagulation indexes, Bilirubin, NH3 and liver enzymes improved. Average treatment time is 13.7 days; The overall mortality rate is 33.3%, of which: 100% are patients with grade 4 hepatic coma; 40% have grade 3 hepatic coma and 7.7% have grade 2 hepatic coma. Common complications are: grade 1,2 anaphylaxis; Electrolyte disorders, thrombocytopenia, bleeding or catheter complications account for 1 - 3.1%. Conclusion: Plasma exchange method improves hepatic coma and multiple organ failure; Improved liver function and fewer serious complications.