ĐÁNH GIÁ HIỆU QUẢ ĐIỀU TRỊ LYMPHOMA KHÔNG HODGKIN DÒNG TẾ BÀO B TRÊN NGƯỜI CAO TUỔI TẠI BỆNH VIỆN CHỢ RẪY

Abstract

Introduction: Non-Hodgkin's Lymphoma (NHL) is the most common disease in hematopoietic malignancies, which can occur at any age, and the incidence increases with age. Similar to the world, the population of Vietnam is aging increasingly. As a result, NHL has become an important cause of morbidity and mortality among the elderly in Vietnam nowadays. However, there are currently not many studies in Viet Nam evaluating the effectiveness of treatment in these patients. Subjects: All patients aged 60 years and older were diagnosed with B-cell non-Hodgkin lymphoma at the Hematology Department - Cho Ray Hospital from January 2017 to December 2020. Research methods: Retrospective, descriptive case series. Results: 56 patients (61-80 years old, mean 68.3 years old) were selected for treatment. 40 patients were treated with R-CHOP regimen and 16 patients were treated with R-CVP regimen. The rate of complete response after 6-8 cycles of chemotherapy was 71.1%, EFS and OS after 2 years of follow-up were 69.6% and 75.2%. Conclusion: Treatment of patients with B-cell non-Hodgkin lymphoma in the elderly at Cho Ray hospital with R-CHOP and R-CVP regimens brought about good results, prolonging survival time for patients. The regimens are relatively safe for elderly patients.