ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG VÀ MỘT SỐ YẾU TỐ LIÊN QUAN ĐẾN CHỈ SỐ HOẠT ĐỘNG BỆNH Ở BỆNH NHÂN VIÊM KHỚP VẢY NẾN

Abstract

Objective: Psoriatic arthritis (PSO) is a chronic inflammatory arthritis that often occurs in patients with psoriasis. The clinical and subclinical characteristics are different from joint diseases such as rheumatoid arthritis, ankylosing spondylitis... leading to difficulties in diagnosis and treatment. The objective of the study is to evaluate the above characteristics and some factors related to disease activity index in PSO patients. Subjects and methods: Cross-sectional, retrospective descriptive study conducted on 62 patients with a confirmed diagnosis of PSO who came for examination or treatment at the National Hospital of Dermatology and Venereology from October 2023 to June 2024. Patients who meet the disease selection criteria have information collected about general, clinical, paraclinical characteristics, DAPSA, VAS, PASI, NASI index. Evaluate the relationship between the above characteristics and disease activity level according to DAPSA and VAS index. Results: Mean age is 50,7; Male/female ratio is approximately 2/1. Mean disease duration is 5,8 years. Pain is the most common clinical symptom (92.1%), followed by joint swelling (59.6%); limited mobility (48.3%) and stiffness (45.2%). Most cases manifest in isolated peripheral joints. The average number of damaged joints is 12 joints/patient. The mean DAPSA and mean VAS scores were 25.3 and 5.4, respectively. Most blood tests are within normal limits. Long disease duration is a factor that increases the rate of moderate/severe DAPSA in the study group. Conclusion: Joint pain is the most common clinical symptom. The research team's CRP test was high, while other blood tests were often within normal limits. Long disease duration increases the rate of moderate-severe disease activity.