THE CONCENTRATION OF SERUM 25(OH)D IN CHILDREN WITH BRONCHIOLITIS TREATED AT THE VIETNAM NATIONAL CHILDREN'S HOSPITAL

Phạm Văn Dương1,, Nguyễn Thị Diệu Thúy1
1 Hanoi Medical University

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Abstract

Vitamin D plays an important role in the immune system, including both innate and adaptive immunity. Objectives: To investigate the concentration of serum 25-(OH)D in children with bronchiolitis and the relationship between the concentration of serum 25-(OH)D and the severity of bronchiolitis. Subjects and methodS: 108 children with bronchiolitis treated at the Vietnam National Children's Hospital from July 2020 to June 2021. This was a descriptive cross-sectional study. Results: Mild bronchiolitis accounted for the highest rate with 62.04% and severe bronchiolitis was 15.74%. There was 14.82% children with bronchiolitis had low serum 25-(OH)D concentrations (< 50 nmol/l). 21.05% of group having serum 25-(OH)D concentrations less than 75 nmol/l suffered from severe bronchiolitis compared with 12.86% in group of serum 25-(OH)D concentrations equal or more than 75 nmol/l, with p=0.022. Conclusion: The serum 25-(OH)D concentration is associated with the severity of bronchiolitis in children.

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References

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