MỐI LIÊN QUAN GIỮA TÌNH TRẠNG VIÊM DA CƠ ĐỊA TRONG 6 THÁNG ĐẦU ĐỜI VỚI ĐỘ ẨM DA VÀ CÁC ĐẶC ĐIỂM LÂM SÀNG CỦA TRẺ LÚC 2 NGÀY TUỔI

Abstract

inflammatory skin disease commonly found in infants. AD is associated with various factors, including skin hydration, family history, and clinical features of the infants at birth. Objective: To investigate the cummulative frequency of AD in the first 6 months of life and the relations with skin hydration status as well as clinical characteristics of infants at 2 days old. Methods: We conducted a longitudinal descriptive study, which followed infants from 2 day-old to 6 months of age. The stratum corneum hydration (SCH), transepidermal water loss (TEWL), family history, and infant features at birth were recorded at 2 days after birth. Dermatitis and atopic dermatitis was monitored during the first 6 months of life. Results: A total of 330 newborns at 2 days old were included in the study; among them, 53 infants were followed up until 6 months of age. The SCH and TEWL measured at 2 day-old were not significantly different among the groups of infants with AD, other dermatitis, and those without dermatitis in the first 6 months of life. The infants with AD in the first 6 months of life had a higher frequency of family history of allergic diseases (p=0.009), higher gestational age (p=0.003), birth weight (p=0.004), and height (p<0.001) compared to those without dermatitis. Conclusion: Atopic dermatitis in the first 6 months of life was associated with a family history of allergic diseases, higher gestational age, birth weight and height of the infants.