DRUG-RELATED PROBLEMS IN PEDIATRIC OUTPATIENTS’ PRESCRIPTIONS AT A HOSPITAL IN KIEN GIANG PROVINCE

Trần Hồng Lam Huỳnh, Thắng Nguyễn, Thị Thuỳ Trang Trần, Thanh Thuý Đỗ, Thị Bé Năm Trần, Duy Khánh Đặng

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Abstract

Background: Drug-related problems are one of the leading causes of treatment failure. Particularly, ensuring the safe and effective use medications for children is utmost importance Objectives: To identify and assess associated factors of drug-related problems in outpatient prescribing at a hospital of Kien Giang province. Materials and methods: A cross-sectional, retrospective descriptive study was conducted on the prescriptions of children from 0 to under 18 years old who were outpatients with health insurance and treated by doctors at a hospital in Kien Giang province. Drug-related problems were identified and classified based on Decision No. 3547/QĐ-BYT in 2021 by the Ministry of Health. Results: In the 323 outpatient prescriptions for pediatric patients surveyed, the rate of at least one drug-related problem was 57,9%. Specifically, the rates of drug-related problems concerning high doses, inappropriate timing of drug administration during the day, and drug interactions were 29,72%, 32.2%, and 0,6%. The number of drugs in the prescription and the age of the pediatric patients were related to the occurrence of drug-related problems (p < 0,05). Conclusion: The rate of drug-related problems in outpatient prescriptions for pediatric patients is quite high. The number of drugs in the prescription and the age of the pediatric patients are factors that increase the risk of drug-related problems in the prescription

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References

1. Bộ Y tế (2021), Quyết định 3547/QĐ-BYT về việc ban hành mẫu phiếu phân tích sử dụng thuốc, Phụ lục 2.
2. Lê Trần Thanh Vy, Nguyễn Thắng, Nguyễn Hương Thảo (2023). Các vấn đề liên quan đến thuốc trong đơn thuốc ngoại trú cho trẻ em tại thành phố cần thơ. Tạp chí Y Dược học Cần Thơ, 28, 148-156
3. Lý Thanh Toàn, Lê Trần Thanh Vy, Ông Huy Thanh, Trương Lê Minh, Nguyễn Thắng, Nguyễn Minh Phương (2022). Một số vấn đề liên quan đến thuốc và một số yếu tố liên quan trong việc kê đơn thuốc ngoại trú ở một bệnh viện nhi tại Cần Thơ. Tạp chí Y Dược học Cần Thơ, 49, 1-8.
4. AlAzmi A.A., AlHamdan H., Ahmed O., et al. (2019), Impact of the e‐prescribing system on the incidence and nature of drug‐related problems in children in a Saudi hospital, Int J Pharm Pract, 27(6), pp.578-581.
5. Jafarian K., Allameh Z., Memarzadeh M., et al. (2019), The Responsibility of Clinical Pharmacists for the Safety of Medication Use in Hospitalized Children: A Middle Eastern Experience”, J Res Pharm Pract, 8(2), pp.83-91.
6. Pharmaceutical Care Network Europe Association (2020), PCNE classification V9.1
7. Paul S., Whibley J., John S. (2011), Challenges in paediatric prescribing, Nurse Prescribing, 9(5), pp.220-226.
8. Wang H. Y. et al. (2017), Cross-sectional investigation of drug-related problems among adults in a medical center outpatient clinic: application of virtual medicine records in the cloud, Pharmacoepidemiol Drug Saf, 26(1), pp.71-80.