CLINICAL AND SUBCLINICAL CHARACTERISTICS AND TREATMENT OUTCOMES OF PYOGENIC LIVER ABSCESS IN TYPE 2 DIABETES
Main Article Content
Abstract
Objective: To describe clinical, subclinical characteristics and treatment outcomes of pyogenic liver abscess in type 2 diabetes. Subject and method: Retrospectively and prospectively study 48 patients were diagnosed with pyogenic liver abscess had positive cultered bacterial in type 2 diabetes which treated at bạch mai Hospital from 1/2022 to 4/2024. Result: The majority of patients presented with fever (94.8%); right upper abdominal pain in (93.1%); In addition to diabetes, other common comorbidities were gallstones (13.8%), alcohol abuse (10.3%); leukocytosis 75%; hypoalbuminemia (63.8%). The average value of Glucose was 12.7 ± 4.3 mmo/l, HbA1c (9.2 ± 1.8%). 69% with a solitary abscess, 79.3% in the right hepatic lobe, 29.3% gas formation. Common bacteriological characteristics were Klebsiella pneumoniae (89.7%) and Escherichia coli 3.4%. The average hospital stay of the patients were 15.3 days, arrange 4 – 52 days. The average number of days without fever is 3.9 days. 67.2% of patients recovered and 32.8% of patients were transferred to lower levels, no patients died. Hyperglycemia, increased CRP, leukocytosis and hypoalbuminemia affect hospital stay. Conclusion: Pyogenic liver abscess in type 2 diabetes has prominent symptoms such as fever, right upper abdominal pain, with a single abscess in the right hepatic lobe and the main bacteriological characteristics is Klebsiella pneumoniae. Hyperglycemia, increased CRP, leukocytosis and hypoalbuminemia affect hospital stay.
Article Details
Keywords
Liver abscess, bacteria, Klebsiella pneumoniae, type 2 diabetes.
References
2. Hà Khắc Trung (2014) Nghiên cứu đặc điểm lâm sàng, cận lâm sàng của áp xe gan do vi khuẩn tại Khoa Tiêu hóa - Bệnh viện Bạch Mai. Luận văn thạc sỹ y học
3. Vũ Huy Bình (2017) Nhận xét đặc điểm lâm sàng, cận lâm sàng và kết quả điều trị áp xe gan do vi khuẩn bằng sondle Pigtail. Luận văn thạc sĩ Y học. Trường đại Y Hà Nội
4. Serraino C et al (2018) Characteristics and management of pyogenic liver abscess: A European experience. Medicine (Baltimore) 97(19): 0628
5. Chen W et al (2008) Clinical outcome and prognostic factors of patients with pyogenic liver abscess requiring intensive care. Crit Care Med 36(4): 1184-1188
6. Kim EJ et al (2019) Diabetes and the risk of infection: A national cohort study. Diabetes Metab J 43(6): 804-814
7. Rahimian J., Wilson T., Oram V. et al (2004). Pyogenic liver abscess: recent trends in etiology and mortality. Clin Infect Dis, 39(11), 1654-9
8. Malik A. A., Bari S. U., Rouf K. A. et al (2010). Pyogenic liver abscess: Changing patterns in approach. World J Gastrointest Surg, 2 (12), 395-401
9. Lee HL et al (2004) Clinical significance and mechanism of gas formation of pyogenic liver abscess due to Klebsiella pneumoniae. J Clin Microbiol 42(6): 2783-2785
10. Soreide Kjetil (2018) Blumgart's Surgery of the liver, Biliary tract and Pancreas. Norwegian Medical Assoc Akersgata 2(1152), OsLo, 0107, Norway