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Date Published: 13/09/2021
Abstract Views: 303
Views PDF: 150
DOI: https://doi.org/10.51298/vmj.v505i2.1132
Issue
Vol. 505 No. 2 (2021)
Section
Các bài báo
How to Cite
Ngọc Kim Ngân, T. ., Phương Thảo, L. ., & Đặng Anh Thư, P. . (2021). THE CHARACTTERISTICS OF B-CELL LYMPHOMAS INVOLVEMENT IN THE BONE MARROW. Vietnam Medical Journal, 505(2). https://doi.org/10.51298/vmj.v505i2.1132

THE CHARACTTERISTICS OF B-CELL LYMPHOMAS INVOLVEMENT IN THE BONE MARROW

Tiêu Ngọc Kim Ngân1,, Lê Phương Thảo1, Phan Đặng Anh Thư2
1 Blood Transfusion Haematology Hospital
2 University of Medicine and Pharmacy at Ho Chi Minh City

Main Article Content

Abstract

Introduction: Bone marrow examination is an integral part of the clinical staging of lymphoma, also prognosis and therapeutic strategies. Objective: This study aimed to evaluate the incidence and characteristics of bone marrow involvement of B-cell lymphoma on trephine biopsy. Subjects and Methods: Cross section description of B-cell lymphoma from January 2019 to December 2020 at Blood Transfusion Hematology Hospital. The incidence and pattern of bone marrow involvement were analyzed. Results: The frequency of bone marrow involvement of B-cell lymphomas was 64.8%. Bone marrow involvement was present in 80% of low-grade B-cell lymphomas, and 40% of high-grade variants. The highest incidence of bone marrow involvement was seen in LPL and BL (100%) and the lowest was found in DLBCL (25.6%). Diffused pattern of infiltration was predominant (53%), followed by mixed pattern (31%). Typical bone marrow involvement in 50% FL and 10% DLBCL (transformed FL to DLBCL) was characterized by paratrabecular infiltration. Intrasinusoidal infiltration was not detected. The most frequent pattern was mixed pattern (72.2%) found in MZL. Conclusion: The frequency of bone marrow involvement of low-grade B-cell lymphomas was higher than high-grade variants. The pattern of diffuse infiltration was predominantly. 

Article Details

Keywords

B-cell lymphoma, paratrabecular infiltration, random focal infiltration, diffuse infiltration, interstitial infiltration, intrasinusoidal infiltration, mixed infiltration

References

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