ĐẶC ĐIỂM PHÂN BỐ VÀ TÍNH KHÁNG KHÁNG SINH CỦA VI KHUẨN ENTEROBACTER SPP. PHÂN LẬP TẠI BỆNH VIỆN ĐA KHOA TỈNH BẮC NINH

Abstract

Objective: Study the distribution and antimicrobial-resistant characteristics of Enterobacter spp. isolated from Bac Ninh Provincial General Hospital in the period from 2019 to 2022. Subject and methods: This was a descriptive study. The subject of the study was Enterobacter spp. strains isolated from Bac Ninh Provincial General Hospital in the period between 2019 and 2022. Results: Out of a total of 74 strains of Enterobacter spp. isolated during the research period from 2019 to 2022, the number of isolates from men accounted for 60.8%, which is 1,5 times higher than the rate from women (39.2%). Respiratory fluid specimens had the highest rate of isolation of Enterobacter (41.9%). The proportion of Enterobacter isolated from wound, urine, and blood was 33.8%, 13.5%, and 10.8%, respectively. The percentage of Enterobacter spp. isolated from the respiratory medicine department was the highest, at 24.3%, followed by the trauma surgery department (16.2%). The rate of Enterobacter spp. isolated from the dermatology department and cardiovascular center was the lowest, at 1.4%. Enterobacter was the most resistant to cefuroxime (66.2%), followed by ceftriaxone (55.2%) and cefotaxime (53.6%). In contrast, Enterobacterspp. was the most sensitive to amikacin (70,3%), followed by imipenem (64.7%), chloramphenicol (64.2%), and piperacillin/tazobactam (60,0%).  Conclusion: The study showed that Enterobacter spp. mainly causes respiratory infections, wound infections, and urinary tract infections. Enterobacter spp. was the most resistant to cefuroxime, ceftriaxone, and cefotaxime. These bacteria were the most sensitive to amikacin, imipenem, and chloramphenicol.