A SURVEY ON DRUG RELATED PROBLEMS IN PATIENTS WITH ACUTE CORONARY SYNDROME AT A CARDIOVASCULAR HOSPITAL IN THE MEKONG DELTA

Trúc Linh Trần, Tân Tố Anh Lê, Đăng Khoa Lý, Thắng Nguyễn

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Abstract

Background: Acute coronary syndrome (ACS) is a severe emergency event of coronary artery disease, the leading cause of cardiovascular death and serious complications later. However, many studies have now shown that the occurrence of drug-related problems (DRPs) can affect patient treatment outcomes. Objective: Determine the rate of some drug-related problems in patients with acute coronary syndrome at a cardiovascular hospital in the Mekong Delta in 2023 - 2024. Research subjects and methods: A cross-sectional and prospective study was conducted on ACS patients, who were followed up at 1 month after discharge, from August 2023 to January 2024. Results: There were 78 patients participating in the study. The mean age of patients was 66.6 years old, and men accounted for twice as many as women (66.7%). The average number of DRPs per prescription at discharge was 1.17 and 1 month after was 1.19. The main DRPs at the two timepoints were: Drug interactions (T1.2) accounting for 42.3% and 29.5% patients; Underdosing (T2.2) 28.2% and 26.9%, DRP for patient compliance in the first month of treatment was 48.7%. Conclusion: DRPs in the treatment of patients with ACS occur at a relatively high rate in the hospital, which can affect the patient's outcomes. Further research should have appropriate interventions to minimize these DRPs.

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References

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