LÂM SÀNG, CẬN LÂM SÀNG BỆNH NHÂN COVID-19 VÀ SỐT RÉT TẠI BỆNH VIỆN BỆNH NHIỆT ĐỚI TRUNG ƯƠNG

Abstract

Objectives: This study aims to describe the clinical manifestation and laboratory results among COVID-19 and malaria patients in 2020.Participants and Methods: We conducted a cross-sectional study on 71 patients include 60 confirmation of SARS-CoV-2 using RT-PCR method and 11 malaria patients at National Hospital for Tropical Diseases. We collected information about clinical and subclinical characteristics by direct interview or extract from medical records. Results: The most common symptoms of malaria patients at admission were fever (90.1%), in COVID-19 patients were 45%, dry cough were common symptoms of COVID-19 patients (75%) and The mean incubation period was 6.53 days. Duration of viral shedding was 8.22± 4.83 days. Clearance of parasitic malaria was 4.18 ± 2.09 days. D-Dimer in malaria patients increased (IQR: 2829 ng/mL compared to 733 ng/ml), with p = 0.002.PCT in malaria patients increased higher than COVID-19 patients (IQR: 1,715 ng/mL compared to 0.028 ng/ml) with p = 0.02. On chest radiographs, we found lung damage in about 75% of patients. The bilateral lung damage was accounted 80%, and mostly seen in the middle and the bottom of the lung. Conclusion: Fever is a common symptom of malaria and COVID-19, should not ignore malaria in COVID-19 pandemic if the patient has epidemiological elements.