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Date Published: 18/11/2024
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DOI: https://doi.org/10.51298/vmj.v544i1.11755
Issue
Vol. 544 No. 1 (2024)
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Các bài báo
How to Cite
Thân, M. H., & Nguyễn, C. T. (2024). THE CLINICAL MANIFESTATONS, LABORATORIES OF PATIENTS WITH PNEUMONIA CAUSED BY ELIZABETHKINGIA ANOPHELIS IN NATIONAL HOSPITAL FOR TROPICAL DISEASES. Vietnam Medical Journal, 544(1). https://doi.org/10.51298/vmj.v544i1.11755

THE CLINICAL MANIFESTATONS, LABORATORIES OF PATIENTS WITH PNEUMONIA CAUSED BY ELIZABETHKINGIA ANOPHELIS IN NATIONAL HOSPITAL FOR TROPICAL DISEASES

Mạnh Hùng Thân, Cường Thạch Nguyễn

Main Article Content

Abstract

Objective: Describe clinical manifestations and laboratories of patients with ventilator-associated pneumonia related to Elizabethkingia anophelis. Subjects and methods: Cross-sectional descriptive study on 73 patients diagnosed and treated for ventilator-associated pneumonia related to E. anophelis at the Central Hospital for Tropical Diseases from January 2020 to May 2024. Data were analyzed by SPSS 20.0 software. Results: Main clinical symptoms: increased sputum secretion (97.3%), dyspnea (94.5%), decreased breath sounds (97.3%), crackles (90.4%). Leukocytosis was found in 58.9% of patients. The majority (63.0%) had infiltrative lesions on chest X-ray. Anemia accounted for 63.0% (of which moderate anemia: 45.2%). Many patients had liver and kidney damage: increase AST (63.0%), ALT (46.6%), increase Urea (46.6%), Creatinine (28.8%). Increased CRP > 10mg/LL accounted for 94.5%, increased PCT > 0.05 ng/L in all patients, 94.4% of patients had increased D-dimer > 500 ng/L. Conclusion: Increased sputum secretion is the most common symptom in patients with ventilator-associated pneumonia associated with E. anophelis. Lesions on chest X-ray were mainly infiltrates, most had leukocytosis and anemia.

Article Details

Keywords

: Ventilator-associated pneumonia, Elizabethkingia anophelis

References

1. Lau, S.K., W.-N. Chow, C.-H. Foo, et al. (2016) Elizabethkingia anophelis bacteremia is associated with clinically significant infections and high mortality. Scientific reports. 6(1): p. 26045.
2. Singh Sr, N., A. Singh, P. Gupta, et al. (2022) Elizabethkingia anophelis Infections: a case series from a tertiary care hospital in Uttar Pradesh. Cureus. 14(11).
3. Choi, M.H., M. Kim, S.J. Jeong, et al. (2019) Risk factors for Elizabethkingia acquisition and clinical characteristics of patients, South Korea. Emerging infectious diseases. 25(1): p. 42.
4. Kalil, A.C., M.L. Metersky, M. Klompas, et al. (2016) Management of adults with hospital-acquired and ventilator-associated pneumonia: 2016 clinical practice guidelines by the Infectious Diseases Society of America and the American Thoracic Society. Clinical infectious diseases. 63(5): p. e61-e111.
5. Nguyễn Quỳnh Phương (2020) Nghiên cứu đặc điểm lâm sàng, cận lâm sàng viêm phổi thở máy do Klebsiella pneumoniae và tính kháng thuốc của vi khuẩn.
6. Lee, Y.-L., K.-M. Liu, H.-L. Chang, et al. (2022) The evolutionary trend and genomic features of an emerging lineage of elizabethkingia anophelis strains in Taiwan. Microbiology Spectrum. 10(1): p. e01682-21.
7. Li, Y., T. Liu, C. Shi, et al. (2022) Epidemiological, clinical, and laboratory features of patients infected with Elizabethkingia meningoseptica at a tertiary hospital in Hefei City, China. Frontiers in Public Health. 10: p. 964046.
8. Nguyễn Văn Dũng. (2022) Nghiên cứu căn nguyên vi khuẩn và đặc điểm viêm phổi liên quan thở máy ở người bệnh điều trị tại khoa hồi sức tích cực, Bệnh viện đa khoa tỉnh Thanh Hóa.
9. Gursel, G. and N. Demir (2006) Incidence and risk factors for the development of acute renal failure in patients with ventilator‐associated pneumonia. Nephrology. 11(3): p. 159-164.
10. Ferrer, M., T. Sequeira, C. Cilloniz, et al. (2019) Ventilator-associated pneumonia and PaO2/FIO2 diagnostic accuracy: changing the paradigm? Journal of clinical medicine. 8(8): p. 1217.