TÌNH TRẠNG KHÁNG KHÁNG SINH CỦA STAPHYLOCOCCUS AUREUS GÂY NHIỄM KHUẨN HUYẾT Ở CÁC BỆNH NHÂN MỚI NHẬP VIỆN ĐIỀU TRỊ TẠI BỆNH VIỆN HỮU NGHỊ ĐA KHOA NGHỆ AN

Abstract

Objectives: Assessing the antibiotic resistance of S. aureus causing bacteremia in newly hospitalized patients at Nghe An General Friendship Hospital. Subjects and methods: Cross-sectional descriptive study on 246 new infectious patients treated at Nghe An General Friendship Hospital with positive blood culture results at the time of admission from September 2021 to September 2023. Results: The rate of bacteremia due to S. aureus accounts for 20.7%. By source of infection: respiratory: 37.3%; skin, soft tissue 29.4%; from 2 infected foci 9.8%; blood 5.9%. Antibiotic resistance rate of S. aureus bacteria resistant to ciprofloxacin 23.4%, levofloxacin 21.7%, gentamycin 34.8%, cefoxitin 66%, methicillin 66%. Resistance to vancomycin and linezolid has not been recorded. MRSA rate 66.7%, MDR S. aureus rate 74.5%, Vancomycin MICs ≥2 pg/l  is 27.5%; Although there were no S. aureus strains resistant to Vancomycin, there were 14 strains with MICs ≥2 pg/l and 3 strains with MICs 2-16 pg/l with Vancomycin. Conclusion: Antibiotic resistance in patients with septicemia caused by Staphylococcus aureus when first hospitalized for treatment at Nghe An General Friendship Hospital is on the rise, but resistance to Vancomycin and Linezolid has not been recorded.