MỐI LIÊN QUAN GIỮA TROPONIN I VỚI TĂNG HUYẾT ÁP VÀ CÁC YẾU TỐ CỦA HỘI CHỨNG CHUYỂN HÓA Ở NGƯỜI BỆNH ĐÁI THÁO ĐƯỜNG TÍP 2

Abstract

Background: Troponin I is a crucial biomarker for detecting myocardial damage and cardiovascular issues early, irrespective of their cause. Given that diabetes and metabolic syndrome elevate the risk of cardiovascular disease, exploring the connection between troponin I levels and these conditions is essential for early cardiovascular disease diagnosis. Method: This study examines troponin I levels in individuals with type 2 diabetes who have hypertension and metabolic syndrome factors but who do not have coronary artery disease or myocardial infarction. The study focuses on patients receiving outpatient treatment at Hoan My Saigon General Hospital and Le Van Thinh Hospital in Ho Chi Minh City. Results: The average age of the survey group was 63.7 years, and the majority were male. The prevalence of 2 to 4 components of MetS was notable. The median troponin I concentration was significantly higher in individuals with MetS (p=0.003) and those with hypertension (p<0.001). For all MetS factors, except for blood glucose levels ≥100 mg/dL, the median troponin I concentration was elevated compared to other groups (p<0.05). Among individuals with MetS, the median troponin I concentration increased progressively with the number of MetS components (p<0.001). Conclusion: troponin I is associated with hypertension, metabolic syndrome (MetS), and its various components. It is a highly valuable biomarker for monitoring myocardial damage and cardiovascular complications, especially in the early stages, in patients with type 2 diabetes who have MetS.