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Date Published: 26/11/2024
Abstract Views: 57
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DOI: https://doi.org/10.51298/vmj.v544i2.11883
Issue
Vol. 544 No. 2 (2024)
Section
Các bài báo
How to Cite
Nguyễn, T. L., Mai, T. H., Phạm, T. T. P., Nguyễn, T. L. H., Phùng, T. H., & Nguyễn, T. Q. N. (2024). EFFICACY OF THE INSURE METHOD IN TREATING RESPIRATORY DISTRESS SYNDROME IN PRETERM INFANTS AT HANOI OBSTETRICS AND GYNECOLOGY HOSPITAL. Vietnam Medical Journal, 544(2). https://doi.org/10.51298/vmj.v544i2.11883

EFFICACY OF THE INSURE METHOD IN TREATING RESPIRATORY DISTRESS SYNDROME IN PRETERM INFANTS AT HANOI OBSTETRICS AND GYNECOLOGY HOSPITAL

Thị Linh Nguyễn, Trọng Hưng Mai, Thị Thu Phương Phạm, Thị Liên Hương Nguyễn, Thị Hải Phùng, Thị Quỳnh Nga Nguyễn

Main Article Content

Abstract

Objective: To evaluate the effectiveness of the INSURE method (INtubate – SURfactant – Extubate) in treating respiratory distress syndrome (RDS) in premature infants at Hanoi Obstetrics and Gynecology Hospital. Patients and methods: This is a descriptive study that included all newborns diagnosed with respiratory distress due to hyaline membrane disease and treated using the INSURE method. Results: Between July 2023 and June 2024, a total of 121 premature infants with respiratory distress syndrome were treated at the neonatal department of Hanoi Obstetrics and Gynecology Hospital, meeting the study's selection criteria. Among these infants, 57 (47.1%) had a gestational age of less than 30 weeks, 48 (39.7%) had a gestational age of 30-32 weeks, and 16 (13.2%) had a gestational age of 32-37 weeks. The average birth weight was 1315±372g, ranging from 700g to 2400g. Antenatal corticosteroids were administered in 76% of pregnancies. Chest X-ray results revealed that 65.3% of the infants had hyaline membrane disease at stage II, and 34.7% were at stage III. Surfactant was administered at an initial dose of 200 mg/kg to 95% of the infants, with no need for a second dose in most cases. Of the infants in the study, 106 (87.6%) were successfully treated with the INSURE method, showing significant improvements in clinical signs, chest X-ray results, and blood gas levels within 6 to 48 hours. The overall mortality rate in the study group was 5.8%, with the group that did not respond successfully to the INSURE method having a higher mortality rate and longer treatment duration compared to the group that responded successfully. Conclusion: The INSURE method has been effectively applied in the treatment of premature infants with a high success rate.

Article Details

Keywords

Respiratory distress syndrome, premature infants, pulmonary surfactant.

References

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