THỰC TRẠNG SỬ DỤNG THUỐC ĐIỀU TRỊ TĂNG HUYẾT ÁP TRÊN BỆNH NHÂN ĐÁI THÁO ĐƯỜNG TÍP 2 TẠI TRUNG TÂM Y TẾ HUYỆN TÂN PHƯỚC NĂM 2021

Abstract

Introduction: Besides hypertension, diabetes is a metabolic endocrine disease that goes hand in hand with cardiovascular diseases, and is also a global social problem, becoming the fourth or third leading cause of death in developed countries and is classified as the fastest growing non-communicable disease in the world. Objective: Analyze the current status of medication use in hypertensive patients with type 2 diabetes at Tan Phuoc Medical Center. Materials and methods: This is a cross-sectional, retrospective, and prospective study with convenient sampling of 300 patients who meet the inclusion and exclusion criteria, based on information collection forms. Results: The study sample included hypertensive patients with an average age of 64.92±10.78 and a male-to-female ratio of 36.3% to 63.7%. Common cardiovascular risk factors in the sample included family history of hypertension, obesity or overweight, and high salt intake. The most commonly used medication was amlodipine with a high proportion of 87.3%, followed by enalapril (14%), losartan (4%), and bisoprolol (3%). Monotherapy accounted for 62.7% of which metformin accounted for the majority at 59.7% and sulfonylureas at 3%. Fatigue was the most commonly reported adverse effect at a rate of 36.7%, followed by headache at 23.7%. Drug interactions were recorded in 56 cases, accounting for 18.7%, of which the most common drug interaction pair was metformin+enalapril at 13.3%. Conclusion: From the study results, we can see that hypertensive patients in the study sample had common cardiovascular risk factors and mostly used amlodipine for treatment. Educating and counseling patients on the importance of treatment adherence can help improve treatment effectiveness and reduce complications related to hypertension.