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THE CLINICAL EFFECTS OF LACTOBACILLUS REUTERI IN SUPPORTING NON-SURGICAL PERIODONTAL TREATMENT
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Abstract
Purpose: Periodontitis is a common oral disease and the leading cause of tooth loss. The aim of the study is to evaluate the clinical effects of tablets containing the probiotic Lactobacillus reuteri (probiotics) in supporting non-surgical treatment (NST) of periodontitis. Materials and methods: 32 patients were randomly divided into 2 groups: test group (probiotics) and control group (placebo). Lozenges are used twice a day for 4 weeks after root planing. A clinical evaluation was performed at baseline (T0), 2 weeks (T1), 1 month (T2), and 3 months (T3) after the treatment. Result: The results showed that at 3 months post-treatment, the test group had periodontal pocket depth in moderate pockets (4-6 mm) and the need for surgery treatments was significantly lower than the control group (p < 0,05). Conclusion: Our results provided evidences of adjunctive effect of probiotics in non-surgical treatment for periodontitis. Using probiotics improves periodontal pocket depth in moderate pockets (4-6 mm) and reduces the need for surgery treatments. As probiotics can be a potential treatment in combination with other periodontal therapies, more studies are needed to promote its clinical application.
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Keywords
periodontitis, probiotics, clinical effects.
References
2. Tekce M, Ince G, Gursoy H, et al. Clinical and microbiological effects of probiotic lozenges in the treatment of chronic periodontitis: a 1‐year follow‐up study. Journal of clinical periodontology. 2015;42(4):363-372.
3. İnce G, Gürsoy H, İpçi ŞD, Cakar G, Emekli‐Alturfan E, Yılmaz S. Clinical and biochemical evaluation of lozenges containing Lactobacillus reuteri as an adjunct to non‐surgical periodontal therapy in chronic periodontitis. Journal of periodontology. 2015;86(6):746-754.
4. Pelekos G, Ho SN, Acharya A, Leung WK, McGrath C. A double‐blind, paralleled‐arm, placebo‐controlled and randomized clinical trial of the effectiveness of probiotics as an adjunct in periodontal care. Journal of Clinical Periodontology. 2019;46(12):1217-1227.
5. Laleman I, Pauwels M, Quirynen M, Teughels W. A dual‐strain Lactobacilli reuteri probiotic improves the treatment of residual pockets: A randomized controlled clinical trial. Journal of clinical periodontology. 2020;47(1):43-53.
6. Citterio F, Gualini G, Chang M, et al. Pocket closure and residual pockets after non‐surgical periodontal therapy: A systematic review and meta‐analysis. Journal of clinical periodontology. 2022;49(1):2-14.
7. Pelekos G, Acharya A, Eiji N, Hong G, Leung WK, McGrath C. Effects of adjunctive probiotic L. reuteri lozenges on S/RSD outcomes at molar sites with deep pockets. Journal of clinical periodontology. 2020;47(9):1098-1107.
8. Martin‐Cabezas R, Davideau JL, Tenenbaum H, Huck O. Clinical efficacy of probiotics as an adjunctive therapy to non‐surgical periodontal treatment of chronic periodontitis: a systematic review and meta‐analysis. Journal of clinical periodontology. 2016;43(6):520-530.