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SYSTEMIC EMBOLIC EVENTS IN LEFT-SIDED INFECTIVE ENDOCARDITIS: PREVALENCE AND RELATED FACTORS
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Abstract
Aim of the study: To determine the rate, the time of occurrence, and the factors associated with embolic events in patients with left-sided infective endocarditis (IE). Patients and methods: Cross-sectional study in patients admitted to the Heart Institute from 01/01/2021 to 31/12/2023 with a diagnosis of IE and left-sided vegetations. Results: 171 patients (118 men, mean age 48,8 ± 16,3 years) were enrolled. The affected valves were mitral in 52%, aortic in 26,3%, and multiple in 21,6% of patients. 38 patients (22,2%) had embolic events (22 before and 16 after initiation of antibotic therapy). There was no association between age, valve position, vegetation number and size, and pathogen agents with embolic events. The cumulative incidence of embolic events rose markedly during week 4 after initiation of antibiotic therapy. Conclusions: In patients with left-sided IE and indication for valve surgery, the operation should be performed before week 4 after initiation of antibiotic therapy
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References
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