PROGNOSTIC VALUE OF THE FIVE-VARIABLE MODEL FOR END-STAGE LIVER DISEASE (5VMELD) FOR PREDICTION OF MORTALITY ON THE PATIENTS WITH LIVER CIRRHOSIS

Virakseth Teng, Ngọc Ánh Trần, Thị Chi Nguyễn

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Abstract

Objective: To evaluate the results of the 5vMELD score in patients with cirrhosis compared with the MELD and MELDNa scores; to investigate the value of the 5VMELD score in prognosis in patients with cirrhosis.Subjects and methods: Cross-sectional descriptive study. The study subjects were patients diagnosed cirrhosis treated at Hanoi Medical University Hospital and Bach Mai Hospital from August 2023 to August 2024. Results: 305 patients were included in the study. The mean age was 57.6 ± 11.0 (16 - 101 years old). The male/female ratio was 5.22/1. The mean 5vMELD score was 21.3 ± 6.4. The 5vMELD score had a weak prognostic value at 30 days with AUROC 0.5259; 90-day medium prognostic value (AUROC 0.6276) (p>0.05). The 5vMELD score had the optimal predictive value at the cutoff point of 21, with a sensitivity of 70%, specificity of 46.78% at 30 days; and a sensitivity of 77.27%, specificity of 48.06% at 90 days. Conclusion: The 5vMELD score has low predictive value in predicting the prognosis of patients with cirrhosis./Further research is needed to determine the significance of the 5vMELD score in predicting the prognosis of patients with cirrhosis.

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References

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