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Date Published: 23/12/2024
Abstract Views: 44
Views pdf: 39
DOI: https://doi.org/10.51298/vmj.v545i3.12343
Issue
Vol. 545 No. 3 (2024)
Section
Các bài báo
How to Cite
Lê, T. H., Lê, T. H. H., Phùng, T. B. T., Trần, D. V., Vũ, T. H., Trần, T. K. D., Nguyễn, T. T. T., & Nguyễn, M. C. (2024). BACTERIAL CO-INFECTION IN PEDIATRIC PATIENTS WITH PNEUMONIA CAUSED BY RESPIRATORY SYNCYTIAL VIRUS. Vietnam Medical Journal, 545(3). https://doi.org/10.51298/vmj.v545i3.12343

BACTERIAL CO-INFECTION IN PEDIATRIC PATIENTS WITH PNEUMONIA CAUSED BY RESPIRATORY SYNCYTIAL VIRUS

Thị Hoa Lê, Thị Hồng Hanh Lê, Thị Bích Thủy Phùng, Duy Vũ Trần, Thị Huyền Vũ, Thị Kim Dung Trần, Thị Thu Thùy Nguyễn, Mạnh Cường Nguyễn

Main Article Content

Abstract

Objective: To determine the etiology of bacterial co-infection in children with respiratory syncytial virus (RSV) pneumonia treated at Vietnam National Children's Hospital. Subjects and methods: A descriptive study was conducted on children aged 1-24 months with community-acquired pneumonia caused by RSV, hospitalized at the Center for Pulmonology and Respiratory Care, Vietnam National Children's Hospital, from August 2022 to June 2024. Results: The detection rate of bacteria in nasopharyngeal samples using Real-time PCR for seven bacteria was 47.3%, while bacterial culture yielded a positive result in 36.9% of cases. Real-time PCR identified H. influenzae as the most common pathogen (53.4%), followed by S. pneumoniae (24%). Co-infection with S. pneumoniae and H. influenzae was found in 15.5% of cases. Bacterial culture identified H. influenzae as the most prevalent pathogen (55.7%), followed by S. pneumoniae (14.4%), M. catarrhalis (11.5%), and S. aureus (10.6%). Both Real-timePCR and bacterial culture were positive in 71/283 (25.1%) cases, while both were negative in 42.8% of cases. Conclusion: Bacterial co-infection is common in children with community-acquired pneumonia caused by RSV. H. influenzae and S. pneumoniae are the most frequent pathogens. Real-time PCR and bacterial culture are commonly used methods, showing relatively high concordance in detecting bacterial co-infection.

Article Details

Keywords

pneumonia, children, respiratory syncytial virus (RSV), bacteria, co-infection

References

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