EFFECTIVENESS OF RADIOFREQUENCY ABLATION (RFA) IN TREATMENT OF BENIGN THYROID NODULES AT CENTRAL HOSPITAL OF ENDOCRINE
Main Article Content
Abstract
Ojectives: "Evaluate the effectiveness of Radiofrequency ablation (RFA) in treatment of benign thyroid nodules and "Identify complications following Radiofrequency Ablation of benign thyroid nodule for 3 months”. Method: A descriptive study with longitudinal follow-up was conducted on 55 patients diagnosed with benign thyroid nodules that being treated with RFA at Central Hospital of Endocrine from August 2023 to April 2024. Results: There was significant decrease of symptom score, cosmetic score, vascularity and thyroid nodule volume after 3 months of treatment. Symptom score 4.05 ± 0.86 decreased to 1.14 ± 0.98, cosmetic score 3.31 ± 0.72 decreased to 2.03 ± 0.19, vascularity 2.83 ± 0.79 reduced to 1.22 ± 0.42, thyroid nodule volume 6.43 ± 2.91 reduced to 3.08 ± 1.64. The decreases were significant with p<0.05. Before treatment, all of patients had symptom scores at morderate level; the cosmetic score was mainly ≥3 and the vascularity were mainly at grade II or higher. After 3 months of RFA, 3.64% patients had moderate symptom scores, 60% patients had mild symptom scores and 36.36% had no symptoms of thyroid nodules (the symptoms were completely gone); the cosmetic score decreased mainly to level 2 (96.36%); The mean volume reduction rate were mainly 60% or more (62.27%) and the vascularity of thyroid nodules decreased to only level I (78.18%) and level II (21.82%). Conclusion: RFA has been shown to be effective and safe in the treatment of benign thyroid nodules.
Article Details
Keywords
Thyroid nodules, Radiofrequency ablation (RFA), safety, effectiveness.
References
2. Ngọ Văn Thọ và Nguyễn Quốc Dũng, Đánh giá hiệu quả điều trị u lành tuyến giáp có điểm thẩm mỹ ≥ 3 bằng đốt sóng cao tần. Tạp chí Điện quang & Y học Hạt nhân. 2022(49):66-72.
3. Nguyễn Tố Ngân và cộng sự, Bước đầu đánh giá hiệu quả phương pháp đốt sóng cao tần nhân lành tính tuyến giáp có triệu chứng. Tạp chí Điện Quang Việt Nam,2019:49-55.
4. Nguyễn Văn Bằng, Nghiên cứu kết quả điều trị nhân giáp lành tính bằng đốt sóng cao tần tại Bệnh viện Đa khoa Gia đình Đà Nẵng. Tạp chí Nội tiết và Đái tháo đường, 2020(38): 67-73.
5. Durante C et al. 2023 European Thyroid Association Clinical Practice Guidelines for thyroid nodule management. European thyroid journal. 2023(12).
6. Fuller CW et al. Radiofrequency ablation for treatment of benign thyroid nodules: systematic review. The Laryngoscope. 2014;124(1):346-353.
7. Hussain I et al, Safety and Efficacy of Radiofrequency Ablation of Thyroid Nodules-Expanding Treatment Options in the United States. Journal of the Endocrine Society. 2021, 5(8).
8. Tang X et al. Evaluation of the safety and efficacy of radiofrequency ablation for treating benign thyroid nodules. Journal of Cancer. 2017;8(5):754-760.
9. Tran NQ, Le BH, Hoang CK, Nguyen HT, Thai TT. Prevalence of Thyroid Nodules and Associated Clinical Characteristics: Findings from a Large Sample of People Undergoing Health Checkups at a University Hospital in Vietnam. Risk management and healthcare policy. 2023(16):899-907.
10. Vu DL, Pham MT, Nguyen VB, Le TM et al, Efficacy and Safety of Radiofrequency Ablation for the Treatment of Autonomously Functioning Thyroid Nodules: A Long-Term Prospective Study. Therapeutics and clinical risk management. 2022(18):11-19.