NGHIÊN CỨU MỐI LIÊN QUAN GIỮA CHỈ SỐ TƯƠNG HỢP THẤT TRÁI – ĐỘNG MẠCH VỚI MỘT SỐ THÔNG SỐ SIÊU ÂM TIM Ở NGƯỜI MẮC BỆNH THẬN MẠN TÍNH GIAI ĐOẠN CUỐI

Abstract

Objective: To investigate the relationship between the left ventricular-arterial coupling index (VAC) and some echocardiographic parameters in patients with end-stage chronic kidney disease (ESKD). Subjects and methods: The study included two groups: the diseased group: 67 patients diagnosed with ESKD and undergoing treatment at Military Hospital 103 from August 2023 to December 2023. Control group: 32 healthy individuals without concomitant cardiovascular diseases. Results: VAC of the ESKD group (3.16 ± 0.94 mmHg/ml and 0.72 ± 0.19) was higher than in the control group (2.76 ± 0.75 mmHg/ml and 0.6 ± 0.08) (p=0.04 and p=0.003). VAC in the Dd  ³ 50 mm group was higher than that in the Dd < 50 mm group (0.76 ± 0.22 and 0.69 ± 0.17, p = 0.02). VAC in the Ds ³ 35 mm group was also significantly increased than in the Ds < 35 mm group (0.84 ± 0.23 and 0.67 ± 0.16, p < 0.01). VAC was correlated positively with GLS (r=0.42, p < 0.001). VAC in the normal GLS group was significantly lower than that in the reduced GLS group. VAC of the EF < 50% group was higher than that of the EF ≥ 50% group (0.98 ± 0.21 and 0.68 ± 0.16, p < 0.01). Conclusion: VAC in end-stage chronic kidney patients was significantly higher than that in the control group. When the left ventricle dilated, VAC increased. VAC also had a positive correlation with GLS. The more EF decreased, the more VAC increased, demonstrating the mismatch between the left ventricle and the artery.