VALUE OF ULTRASOUND-GUIDED FINE NEEDLE ASPIRATION IN DIAGNOSIS OF FOCAL PANCREATIC LESIONS
Main Article Content
Abstract
Confirmation of the nature of focal pancreatic lesions plays a pivotal role in treatment. There are many different types of sampling procedures such as ultrasound-guided fine needle aspiration (US FNA), endoscopic ultrasound-guided fine needle aspiration (EUS FNA), surgical biopsy, ultrasound guided biopsy and computed tomography. We reviewed 18 consecutive ultrasound-guided fine-needle aspiration cytological sampling procedures for focal pancreatic lesions. Result: median number of aspiration was 1.4 times/patient, painless was seen in 17/18 patients. Sensitivity, specificity, positive prediction value and negative prediction value of US FNA in diagnosis pancreatic cancer were 90.9%, 100%, 100%, 87.5% and 94.4%, respectively. No complications related to US-FNA were noted. Conclusion: US FNA cytological sampling is safe and effective for the diagnosis and planning of management of focal pancreatic lesions, especially pancreatic cancer.
Article Details
Keywords
focal pancreatic lesions, US FNA, pancreatic cancer
References
2. Zamboni GA, D’Onofrio M, Idili A, et al. Ultrasound-Guided Percutaneous Fine-Needle Aspiration of 545 Focal Pancreatic Lesions. Am J Roentgenol. Published online November 23, 2012. doi:10.2214/AJR.09.2958
3. Chung JB, Chung DK, Kim DY, et al. Percutaneous Fine Needle Aspiration Biopsy of Pancreatic Cancer Guided by Ultrasonography. Korean J Intern Med. 1989;4(2):125-129. doi:10.3904/kjim.1989.4.2.125
4. Zamboni GA, D’Onofrio M, Idili A, et al. Ultrasound-Guided Percutaneous Fine-Needle Aspiration of 545 Focal Pancreatic Lesions. Am J Roentgenol. 2009;193(6):1691-1695. doi:10.2214/ AJR.09.2958
5. Okasha HH, Naga MI, Esmat S, et al. Endoscopic Ultrasound-Guided Fine Needle Aspiration versus Percutaneous Ultrasound-Guided Fine Needle Aspiration in Diagnosis of Focal Pancreatic Masses. Endosc Ultrasound. 2013; 2(4):190-193. doi:10.4103/2303-9027.121239
6. D’Onofrio M, De Robertis R, Barbi E, et al. Ultrasound-guided percutaneous fine-needle aspiration of solid pancreatic neoplasms: 10-year experience with more than 2,000 cases and a review of the literature. Eur Radiol. 2016;26(6):1801-1807. doi:10.1007/s00330-015-4003-x
7. Matsubara J, Okusaka T, Morizane C, Ikeda M, Ueno H. Ultrasound-guided percutaneous pancreatic tumor biopsy in pancreatic cancer: a comparison with metastatic liver tumor biopsy, including sensitivity, specificity, and complications. J Gastroenterol. 2008;43(3):225-232. doi:10.1007/ s00535-007-2142-9
8. Ultrasound-guided percutaneous procedures in pancreatic diseases: new techniques and applications. Accessed September 9, 2021. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342746/