ĐÁNH GIÁ HIỆU QUẢ ĐIỀU TRỊ KHÔ MẮT SAU PHẪU THUẬT PHACO BẰNG DIQUAFOSOL SODIUM 3% TẠI BỆNH VIỆN MẮT TRUNG ƯƠNG

Abstract

Purpose: To evaluate the effectiveness of treating dry eyes after Phaco surgery with diquafosol sodium 3% eye drops. Subjects and methods: Clinical description, prospective study, uncontrolled group. The study was conducted on 56 eyes (41 patients) with dry eyes after Phaco surgery 1 week from August 2024 to February 2025 in the Viet Nam Institute Ophthology. Patients were treated with diquafosol sodium 3% eye drops 6 times/day and re-examined after 4 weeks, 8 weeks and 12 weeks of treatment. The monitoring indicators included OSDI score, TBUT, Schirmer I test, tear menicus height, and fluorescein and lissamingreen staining score. Results: The study included 2 eyes with grade 1 dry eye, 34 eyes with grade 2 dry eye and 24 eyes with grade 3 dry eye after Phaco surgery 1 week. The average age of 41 patients was 64.5±9.9 years. The OSDI scores before and after treatment 4 weeks, 8 weeks, 12 weeks with diquafosol 3% were 31.4±8.2 points; 29.6±5.3 points; 25.6±5.1 points; 23.5±5.8 points, respectively (p<0.01). The average TBUT before treatment was 4.8±1.5 seconds, increasing to 5.6±1.2 seconds after 4 weeks, 6.9±1.2 seconds after 8 weeks and 7.6±1.8 seconds after 12 weeks (p<0.01). Total tear secretion increased gradually after treatment, with the pre-treatment Schirmer I test were 6.5±2.4 mm, reached 6.8±2.1 mm; 7.3±1.9 mm; 9.3±2.6 mm after 4, 8, and 12 weeks treatment, respectively (p<0.01). The fluorescein staining score on the cornea gradually decreased from 6.7±2.3 points before treatment to 3.5±1.6 points after 12 weeks treatment (p<0.01). The severity of dry eye gradually decreased at the examination times after treatment. Conclusion: Diquafosol sodium 3% is effective in treating dry eye after Phaco surgery.