TỶ LỆ ĐỒNG Ý THỰC HIỆN XÉT NGHIỆM KHẢO SÁT ĐỘT BIẾN GEN ĐÁNH GIÁ NGUY CƠ UNG THƯ DI TRUYỀN TRÊN BỆNH NHÂN UNG THƯ VÚ ĐẾN KHÁM TẠI BỆNH VIỆN QUÂN Y 175

Abstract

Background: Germline genetic testing among patients with breast cancer has an important role in screening, preventing, and treating breast cancer. Understanding the prevalence and the factors associated with intention-to-test improves the effectiveness of genetic counseling. Objectives: To determine the prevalence and the factors associated with intended to participate in genetic testing for breast cancer susceptibility. Methods: A descriptive study of a series of surveys on 292 patients with breast cancer who visited Military Hospital 175 from October 2023 to March 2024. Results: The prevalence of participants intending to undergo genetic testing for breast cancer susceptibility was 64% (95% CI: 58.5-69.5). Multivariate results showed that the associated factors with intention to test included: receiving genetic counseling from a physician (POR* = 3.16), family income over 10 million VND/month (POR*= 2.67), having daughters (POR*= 2.09), attitude score about testing (POR* = 1.39), age group (POR*= 0.33), having a religion (POR* = 0.45). Conclusions: The prevalence of participants intending to undergo genetic testing for breast cancer susceptibility is quite high if the cost is within affordability. However, this rate may be different if the price of the test is changed or after the patients receive genetic counseling.