TÁC ĐỘNG CỦA THỜI ĐIỂM THỰC HIỆN NỘI SOI MẬT TỤY NGƯỢC DÒNG ĐẾN KẾT QUẢ ĐIỀU TRỊ VIÊM TỤY CẤP DO SỎI ỐNG MẬT CHỦ

Abstract

Background: Choledocholithiasis (common bile duct stones) is one of the leading causes of acute pancreatitis, with a high rate of severe progression and mortality. The combination of medical treatment and endoscopic retrograde cholangiopancreatography (ERCP) has contributed to reducing mortality rates. However, the optimal timing for ERCP remains controversial in optimizing treatment outcomes. Objectives: To describe the clinical and subclinical characteristics of patients with acute pancreatitis caused by choledocholithiasis and evaluate the impact of ERCP timing on the treatment outcomes of acute pancreatitis due to choledocholithiasis. Materials and methods: A prospective cross-sectional study was conducted on 53 patients diagnosed with acute pancreatitis due to choledocholithiasis who underwent ERCP at Can Tho Central General Hospital from January 2024 to February 2025. Results: The mean age of patients was 63.8 ± 19.4 years, with 63.5% being 60 years or older. Female patients accounted for 74%, approximately three times the number of male patients. Abdominal pain was present in all patients (100%). The rate of acute pancreatitis with concomitant cholangitis was 45.3%. The overall success rate of ERCP was 98.1%. Early ERCP intervention within 24 hours significantly improved clinical symptoms (p<0.001). ERCP performed within 48 hours reduced hospital stay duration (p=0.008) and facilitated earlier symptom resolution (p=0.005). Post-ERCP complication rate was 3.8%. Conclusion: Early ERCP intervention within the first 48 hours for acute pancreatitis due to choledocholithiasis helps improve clinical symptoms and reduces hospital stay duration. ERCP is an effective treatment modality with a high success rate and a low complication rate.