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EFFICACY OF AUTOGENOUS DENTIN GRAFTING ON BONE DEFECTS AND POSTOPERATIVE COMPLICATIONS AFTER TOOTH EXTRACTION: A SYSTEMATIC REVIEW AND META-ANALYSIS
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Abstract
Background: Tooth extraction is one of the most common surgical procedures in oral and maxillofacial surgery. However, it can lead to complications such as bone defects, alveolar ridge resorption, and delayed healing. Various grafting materials have been used to promote bone regeneration, among which autogenous dentin graft (ADG) has emerged as a promising alternative due to its osteoinductive and osteoconductive properties. Objective: This systematic review and meta-analysis aimed to collectively summarize the available evidence on the use of ADG in socket preservation following tooth extraction. Methods: A literature search was performed in PubMed, Scopus, and Cochrane Library to identify randomized clinical trials that evaluated ADG compared to conventional procedure. Nine studies were included in the meta-analysis. Results: ADG significantly reduces probing depth of distal lower second molar (standardized mean difference (SMD) -1.7, 95% confidence interval (CI) -2.27 – -1.12, p < 0.0001) and significantly increase bone density (SMD 0.59, 95% CI 0.08 to 1.1, p = 0.0227) when compared to the control at 3 months and 6 months postoperatively. Conclusion: Within the limitations, this study showed that ADG could be an effective alternative to other grafting materials for socket preservation, utilizing extracted teeth to produce a biocompatible material that supports bone regeneration.
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Keywords
autogenous dentin graft, socket preservation, systematic review, meta-analysis, bone regeneration
References
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