OUTCOMES OF SPLENECTOMY IN THE TREATMENT OF CHRONIC PRIMARY IMMUNE THROMBOCYTOPENIA IN CHILDREN AT THE NATIONAL INSTITUTE OF HEMATOLOGY AND BLOOD TRANSFUSION, 2020–2023
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Abstract
Background: Splenectomy Outcomes in Pediatric Chronic ITP: 2020–2023, National Institute of Hematology and Blood Transfusion. Objectives: Evaluation of splenectomy effectiveness in pediatric chronic primary immune thrombocytopenia at the National Institute of Hematology and Blood Transfusion (2020–2023). Subjects and methods: A retrospective descriptive study with longitudinal follow-up was conducted on 26 pediatric patients, aged 5 to 16 years, diagnosed with primary chronic immune thrombocytopenia, who underwent splenectomy as a treatment modality. Results: Response rates were 88.5% at 1 week, 80.8% at 1 month, 73.1% at 6 months, and 69.2% at 1 year, with a 57.7% complete response at 1 year without additional therapy. Severe infections occurred in 2 cases (0,07%), with no thrombosis reported. Conclusions: Splenectomy is an effective treatment for pediatric chronic immune thrombocytopenia, with a one-year response rate of 69.2%. Infectious complications occur at a low rate (7,7%).
Keywords
Immune thrombocytopenic purpura, chronic, children, splenectomy
Article Details
References
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