EVALUATION THE CORRELATION OF THE APE, AFP-L3, PIVKA-II WITH CLINICAL AND SUBCLINICAL FACTORS OF HEPATITIS C PATIENTS
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Abstract
Aims: To describe some clinical and subclinical characteristics of hepatitis C patients; evaluated the correlation of AFP, AFP - L3 and PIVKA-II with the characteristics of hepatitis C patients. Patients and methods: A prospective descriptive study on 33 hepatitis C patients. Results: Male patients accounted for the majority, the male/female ratio was 2/1, the average age of both men and women was 53.7 years old. Among hepatitis C patients, alcoholism was the highest rate of 39.4%. Common clinical symptoms were anorexia, fatigue, and abdominal distension. Indicators higher than normal values were AST 173.5 ± 449 U/L, ALT 121.8 ± 258.4 U/L. In the group of patients with tumor, one of the three markers AFP, AFP-L3, PIVKA-II exceeded the threshold rate was 87.5%, in the group of patients without tumor, all three indexes below the threshold was 22.2%. Conclusions: AFP, AFP-L3and PIVKA-II values were elevated in the majority of hepatitis C patients with tumors.
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References
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