COMORBIDITY PATTERNS AND ASSOCIATED HEALTHCARE COSTS IN PATIENTS WITH TYPE 2 DIABETES MELLITUS: A CROSS – SECTIONAL STUDY AT NGUYEN TRAI HOSPITAL, HO CHI MINH CITY

Như Nguyễn Tuyết, Hiền Nguyễn Võ Thu, Nguyên Trần Thị Hồng, Đoan Dương Thị Hồng, Nga Nguyễn Thị Quỳnh

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Abstract

Background: Type 2 diabetes mellitus (T2DM) is a common chronic disease frequently accompanied by multiple comorbidities, which increase treatment costs and complicate disease management. This study aimed to analyze the comorbidity patterns and associated treatment costs in patients with T2DM at Nguyen Trai Hospital, Ho Chi Minh City. Methods: A retrospective cross-sectional study was conducted using outpatient medical records at Nguyen Trai Hospital in 2023. Data included 127,316 T2DM treatment visits, which were matched 1:1 with a non-T2DM control group using propensity score matching (PSM). Comorbidities and costs were analyzed using descriptive statistics, Chi-square and Mann–Whitney U tests, and generalized linear regression models (GLM). Results: The average age of T2DM patients was 65.06 ± 10.18 years, with 54.76% being female. The average number of comorbidities was significantly higher in the T2DM group than in the control group (5.81 vs. 4.61; p < 0.001). The most common comorbidities were hypertension (I10: 89.34%) and dyslipidemia (E78: 85.96%). The average total treatment cost in the T2DM group was 620,588 VND, significantly higher than that of the non-T2DM group (411,833 VND; p < 0.001). Regression analysis indicated that the number of comorbidities was the strongest predictor of treatment costs. Certain comorbidities such as heart failure, chronic kidney disease, and urolithiasis were associated with particularly high treatment costs. Conclusion: Patients with T2DM bear a higher comorbidity burden and incur higher treatment costs than those without the disease. Effective management of comorbidities is key to controlling costs and improving treatment outcomes for T2DM in the context of an increasing disease burden.

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References

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