CLINICAL FEATURES, TREATMENT RESULTS OF LOWER EXTREMITY ARTERY DISEASE AND ASSOCIATED RISK FACTORS IN TYPE 2 DIABETIC PATIENTS WITH CORONARY ARTERY STENOSIS AT CAN THO CENTRAL GENERAL HOSPITAL, 2024–2025

Minh Kiệt Lưu, Văn Truyền Ngô

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Abstract

Background: Lower extremity artery disease (LEAD) is a common manifestation of peripheral artery disease, typically associated with systemic atherosclerosis and an increased risk of cardiovascular events, particularly coronary artery disease (CAD). Objective: To describe clinical characteristics and evaluate treatment outcomes of LEAD and related risk factors in patients with type 2 diabetes mellitus (T2DM) and concomitant CAD. Materials and Methods: A cross-sectional study was conducted on 49 T2DM patients with CAD, admitted to the Interventional Cardiology Department of Can Tho Central General Hospital from November 2024 to April 2025. The ankle-brachial index (ABI) was measured before and one month after treatment. Results: The mean age was 67.06 ± 9.53 years, with 73.47% aged ≥60. There was a statistically significant difference in ABI values between patients aged <60 and ≥60 years (p<0.05), with lower ABI in the older group. ABI values were also significantly lower in limbs with more extensive arterial lesions as assessed by Doppler ultrasound (p<0.05). After one month of treatment, ABI and Fontaine classification improved significantly (p<0.001). Conclusion: The study highlights the importance of a multi-factorial management strategy in treating LEAD in T2DM patients with coexisting CAD, as evidenced by significant improvements in clinical and hemodynamic outcomes.

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References

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