EXAMINATION THE ROLE OF VISUAL EVOKED POTENTIAL IN DIAGNOSIS AND PROGNOSIS OF TRAUMATIC OPTIC NEUROPATHY

Xuân Trang Trịnh , Thị Phương Thúy Đào, Chí Trung Thế Truyền Nguyễn, Vân Hạnh Hoàng, Mạnh Hùng Nguyễn, Hữu Hiếu Lê, Kế Tổ Trần

Main Article Content

Abstract

Purpose: To assess the value of visual evoked potentials (VEPs) in diagnosing optic nerve injury and predicting visual recovery in patients with traumatic optic neuropathy. Method: A prospective observational study was conducted on 29 patients aged 18 to 60 years with traumatic optic neuropathy, in whom PVEP and FVEP were measured at Military Hospital 175. Result: Compared to the unaffected eyes, the traumatized eyes showed significantly reduced amplitudes and prolonged latencies of both PVEP and FVEP. There was a moderate to strong positive correlation between the initial PVEP (r = 0.575) and FVEP (r = 0.603) amplitudes and visual acuity at 8 weeks post-injury, demonstrating the prognostic value of visual evoked potentials. Conclusion: Visual evoked potential (VEP) is an objective and clinically meaningful tool for evaluating optic nerve injury and predicting visual recovery in traumatic optic neuropathy. Both PVEP and FVEP are valuable and can be flexibly applied depending on the clinical context.

Article Details

References

Miller NR. Traumatic Optic Neuropathy. J Neurol Surg B Skull Base. Feb 2021;82(1):107-115. doi:10.1055/s-0040-1722632
2. Gupta S, Tripathi A, Gupta G. Prognosticators for Visual Outcome in Indirect Traumatic Optic Neuropathy: A Prospective Cohort Study. Cureus. Feb 2023;15(2): e35344. doi:10.7759/cureus. 35344
3. Tabatabaei SA, Soleimani M, Alizadeh M, et al. Predictive value of visual evoked potentials, relative afferent pupillary defect, and orbital fractures in patients with traumatic optic neuropathy. Clin Ophthalmol. 2011;5:1021-6. doi:10.2147/opth.S21409
4. Zheng X, Xu G, Zhang K, et al. Assessment of Human Visual Acuity Using Visual Evoked Potential: A Review. Sensors (Basel). Sep 28 2020;20(19)doi:10.3390/s20195542
5. Lê Minh Tuấn Nguyễn Lễ. Ứng dụng điện thế gợi thị giác trong chẩn đoán bệnh lý thị thần kinh do chấn thương. Luận văn Thạc sĩ Đại học Y Dược TP Hồ Chí Minh 2007.
6. Nguyễn Hằng Lan. Nghiên cứu điện thế kích thích thị giác của người bình thường tuổi 20–50. Luận văn Thạc sĩ. Đại học Y Hà Nội 2003.
7. Ekayanti MS, Mahama CN, Ngantung DJ. Normative values of visual evoked potential in adults. Indian J Ophthalmol. Sep 2021;69(9): 2328-2332. doi:10.4103/ijo.IJO_2480_20
8. Mohammed MA, Mossallam E, Allam IY. The role of the flash visual evoked potential in evaluating visual function in patients with indirect traumatic optic neuropathy. Clinical Ophthalmology. 2021:1349-1355.
9. Holmes MD, Sires BS. Flash visual evoked potentials predict visual outcome in traumatic optic neuropathy. Ophthalmic Plast Reconstr Surg. Sep 2004;20(5):342-6. doi:10.1097/ 01.iop.0000134272.55294.4c.