TOTAL AORTIC ARCH REPLACEMENT USING THORAFLEX DEVICES IN THE TREATMENT OF AORTIC DISSECTION

Thành Luân Nguyễn , Tuấn Vũ Lê, Đình Đức Anh Trương, Thị Thẩm Nguyễn, Đoàn Ngọc Bách Nguyễn, Tất Cường Lê, Văn Bảo Nguyễn, Trần Vỹ Trịnh , Hoài Bảo Trương, Thái An Nguyễn

Main Article Content

Abstract

Objective: To evaluate the clinical characteristics, imaging diagnostics, and surgical outcomes of total aortic arch replacement using Thoraflex devices for the treatment of aortic dissection at Chợ Rẫy Hospital. Methods: A retrospective case series. Results: From September 2021 to June 2025, 44 patients with aortic dissection underwent aortic arch replacement using Thoraflex devices. 72,7% Stanford type A and 27,3% Stanford type B aortic dissection. Concomitant procedures included 6,8% with Tirone David operation and 6,8% with CABG. The average aortic cross-clamp time was 121.8 ± 40.03 minutes, Circulation arrest time was 42.51 ± 12.62 minutes, and operative time was 6.1 hours. Postoperative complications included new stroke (4,5%), spinal cord injury (6,8%), renal failure requiring dialysis (11,4%), and mortality (4,5%). The distal end of the stent graft was positioned at or above T8 in 93,2%, with complete thrombosis in segment A (97,7%), partial thrombosis in segment B (72.7%), and no thrombosis in segment C (86.4%). Postoperative aortic remodeling was positively confirmed in 100% of CT scans. Conclusion: Total aortic arch replacement using Thoraflex devices for treating aortic dissection at Chợ Rẫy Hospital demonstrates safety with a 4,5% mortality rate and effectiveness with 100% positive aortic remodeling post-surgery.

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References

1. Czerny M, Schmidli J, Adler S, et al. Current options and recommendations for the treatment of thoracic aortic pathologies involving the aortic arch: an expert consensus document of the European Association for Cardio-Thoracic surgery (EACTS) and the European Society for Vascular Surgery (ESVS). Eur J Cardiothorac Surg. Jan 1 2019;55(1):133-162.doi:10.1093/ejcts/ezy313
2. Dohle DS, Tsagakis K, Janosi RA, et al. Aortic remodelling in aortic dissection after frozen elephant trunkdagger. Eur J Cardiothorac Surg. Jan 2016;49(1):111-7. doi:10.1093/ejcts/ezv045
3. Ma WG, Zheng J, Sun LZ, Elefteriades JA. Open Stented Grafts for Frozen Elephant Trunk Technique: Technical Aspects and Current Outcomes. Aorta (Stamford). Aug 2015;3(4):122-35.doi:10.12945/j.aorta.2015.14.062
4. Phung DHS, Nguyen TS, Vo HL, et al. A novel modification of frozen elephant trunk technique: unique protocol from one institution. Eur Rev Med Pharmacol Sci. Jul 2021;25(14):4738-4745. doi:10.26355/eurrev_202107_26384
5. Preventza O, Liao JL, Olive JK, et al. Neurologic complications after the frozen elephant trunk procedure: A meta-analysis of more than 3000 patients. J Thorac Cardiovasc Surg. Jul 2020; 160(1): 20-33 e4.doi:10.1016/j.jtcvs.2019. 10.031
6. Shrestha M, Kaufeld T, Beckmann E, et al. Total aortic arch replacement with a novel 4-branched frozen elephant trunk prosthesis: Single-center results of the first 100 patients. J Thorac Cardiovasc Surg. Jul 2016;152(1):148-159 e1.doi:10.1016/j.jtcvs.2016.02.077
7. Sun L, Qi R, Zhu J, Liu Y, Zheng J. Total arch replacement combined with stented elephant trunk implantation: a new "standard" therapy for type a dissection involving repair of the aortic arch? Circulation. Mar 8 2011;123(9):971-8. doi:10.1161/CIRCULATIONAHA.110.015081
8. Yamamoto H, Kadohama T, Yamaura G, Tanaka F, Takagi D, Kiryu K, Itagaki Y. Total arch repair with frozen elephant trunk using the "zone 0 arch repair" strategy for type A acute aortic dissection. J Thorac Cardiovasc Surg. Jan 2020; 159(1): 36-45. doi:10.1016/j.jtcvs.2019. 01.125