ĐÁNH GIÁ KẾT QUẢ XẠ TRỊ TOÀN NÃO ĐIỀU TRỊ CÁC TỔN THƯƠNG UNG THƯ PHỔI KHÔNG TẾ BÀO NHỎ DI CĂN NÃO

Abstract

Lung cancer is one of three most common cancer disease and also is main cause of mortality world-wide. It includes two main types, one is small cell lung cancer (SCLC) and the other is non-small cell lung cancer (NSCLC). Advanced stage-lung cancer normally develops brain metastasis. There have been many different clinical trials to evaluate results of whole brain radiotherapy alone (WBRT Alone) in treatment of lung cancer’s brain metastasis and compared with other therapies. It’s shown that WBRT Alone can help to manage and to reduce the symptoms of intra-cranial pressure so that the patients’ life-quality improved. Patients and methods: Including 32 patients NSCLC with brain metastasis. There are from one to three lesions with maximum diameter ≤ 30mm. WBRT Alone with 30Gy, the fraction is 3Gy/day and 5 days/week. The results were evaluated after radiotherapy. Results: 6,2% brain metastasis disappeared completely. The sizes of brain metastasis lesions reduces 53,2% and also 96,9% of those are controlled. After WBRT Alone was given, 84,4% of patients’PS are improved and also subjective symptoms of 62,5% of patients reduced and 12,5% of patients among them without any symptoms. Conclusion: WBRT could help to manage and to reduce the symptoms of intra-cranial pressure so that the patients’ life-quality are improved.