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STAPHYLOCOCCUS EPIDERMIDIS AND IT’S ANTIBIOTIC RESISTANCE ON THE SKIN OF UMBILICUS AND GROIN OF PRE-SURGERY PATIENTS AT UNIVERSITY MEDICAL CENTER IN HO CHI MINH CITY
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Abstract
Background: Staphylococcus epidermidis (S.epidermidis) an important opportunistic infection, most commonly on skin of patients who have had surgical interventions. Study shows that the antibiotic resistance of S. epidermidis is more serious. Objective: To determine percentage of S .epidermidis isolated on the skin of umbilicus and groin of pre-surgery patients and the rate resistance to antibiotics. Methods: Collecting 654 specimens with sterile cotton swabs from the skin of umbilicus or groin of 218 patients at three-time points: after the patient is bathed and anesthetized (1st time), after the nurse washes the skin (2nd time), after the surgeon disinfects the skin (3rd time). Carrying out culture, identification by biochemical test kit for Staphylococci and BD PhoenixTM M50 automatic system, and testing the routine antibiotic susceptibility by the disc diffusion method with 654 samples. Results: Prevalences of S. epidermidis isolated on the umbilicus at three-time points: 33.1% (1st time); 10.2% (2nd time) and 1.8% (3rd time). Prevalences of S. epidermidis isolated on the groin at three-time points: 32.7% (1st time); 9.6% (2nd time) and 1.9% (3rd time). The rate of antibiotic resistance of S. epidermidis over three-time points of specimen collection: penicillin (83.3%; 95.5% and 100%); erythromycin (72.2%; 86.4% and 100%); oxacillin (58.3%; 59.1% and 75%); trimethoprim-sulfamethoxazole (36.1%; 59.1% and 75%); ciprofloxacin (30.6; 36.4 and 0%); clindamycin (16.7%; 22.7% and 50%); levofloxacin (22.2%; 22.7% and 0%); tetracycline (19.4%; 22.7% and 0%); gentamycin (20.8%; 13.6% and 25%); doxycycline (1.4%; 0% and 0%). Particularly 100% of isolated strains of S. epidermidis are sensitive to linezolid. Conclusions: The percentages of S. epidermidis defected on the deinfected skin of umbilicus and groin at 3rd time are 1.8% and 1.9%. S. epidermidis is resistant to many antibiotics, from 75% to 100% with penicillin, erythromycin and oxacillin but still sensitive to linezolid.
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Keywords
S. epidermidis, antibiotic resistance, pre-surgery patients
References
2. Chabi R, Momtaz H (2019), "Virulence factors and antibiotic resistance properties of the Staphylococcus epidermidis strains isolated from hospital infections in Ahvaz, Iran", Tropical medicine and health, 47 (1), pp. 1-9.
3. CLSI (2020), "Performance Standards for Antimicrobial Susceptibility Testing", 30th ed, CLSI supplement M100. Wayne, PA: Clinical and Laboratory Standards Institute; 2020, pp. 58-66.
4. Decousser JW, Desroches M, Bourgeois NN, et al (2015), "Susceptibility trends including emergence of linezolid resistance among coagulase-negative staphylococci and meticillin-resistant Staphylococcus aureus from invasive infections", International journal of antimicrobial agents, 46 (6), pp. 622-630.
5. Deplano A, Vandendriessche S, Nonhoff C, et al (2016), "National surveillance of Staphylococcus epidermidis recovered from bloodstream infections in Belgian hospitals", Journal of Antimicrobial Chemotherapy, 71 (7), pp. 1815-1819.
6. Dortet L, Glaser P, Kassis CN, et al (2018), "Long-lasting successful dissemination of resistance to oxazolidinones in MDR Staphylococcus epidermidis clinical isolates in a tertiary care hospital in France", Journal of Antimicrobial Chemotherapy, 73 (1), pp. 41-51.
7. Eftekhar F, Dadaei T (2011), "Biofilm formation and detection of icaAB genes in clinical isolates of methicillin resistant Staphylococcus aureus", 14 (2), pp. 132-136.
8. Mansson E, Tevell S, Nilsdotter AA, et al (2021), "Methicillin-Resistant Staphylococcus epidermidis Lineages in the Nasal and Skin Microbiota of Patients Planned for Arthroplasty Surgery", Microorganisms, 9 (2), pp. 265.