TREATMENT OUTCOMES CHOLEDOCHOLITHIASIS-ASSOCIATED CHOLANGITIS MANAGED BY ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY AT BACH MAI HOSPITAL, 2024–2025
Main Article Content
Abstract
Objective: This study was conducted to evaluate the treatment outcomes of patients with cholangitis caused by common bile duct (CBD) stones managed by endoscopic retrograde cholangiopancreatography (ERCP) at Bach Mai Hospital during the period of 2024–2025. Methods: A descriptive cross-sectional study with both retrospective and prospective data collection was conducted on 125 inpatients diagnosed with cholangitis due to CBD stones. The study took place at the Department of Gastroenterology and Hepatology, Bach Mai Hospital, from August 2024 to May 2025. The results: Post-intervention laboratory markers significantly improved, including reductions in white blood cell count, C-reactive protein (CRP), total bilirubin, and liver enzymes (AST, ALT), with statistically significant differences (p < 0.01). The success rate of papillary cannulation was 97.6%; complete stone removal was achieved in 88.5% of cases, and partial removal in 8.2%. Biliary stenting was performed in 45.1% of patients. The complication rates following ERCP were: post-ERCP bleeding (4.1%), acute pancreatitis (1.6%), and no cases of duodenal perforation were reported. The rate of good clinical outcomes at discharge was 81.6%. Conclusion: ERCP is a safe and effective therapeutic modality for the management of cholangitis due to common bile duct stones.
Article Details
Keywords
Cholangitis, common bile duct stone, endoscopic retrograde cholangiopancreatograph, ERCP.
References
2. Chen L, Wu Z, Guo C, Wang G, Tu K, Jiang J. Evaluation of Clinical Indications of Three Treatments for Choledocholithiasis with Acute Cholangitis. Int J Gen Med. 2023;16:4669-4680. doi:10.2147/IJGM.S429781
3. Kỳ TD, Quang PMN, Tuấn NA, Tùng NL, Thanh TV, Bình MT. Đánh giá hiệu quả và an toàn của phương pháp nội soi mật tụy ngược dòng điều trị sỏi đường mật tại Bệnh viện Trung ương Quân đội 108. Journal of 108 - Clinical Medicine and Phamarcy. Published online October 25, 2023. doi:10.52389/ydls.v18i7.2046
4. Liang CM, Chiu YC, Lu LS, et al. Early and Direct Endoscopic Stone Removal in the Moderate Grade of Acute Cholangitis with Choledocholithiasis Was Safe and Effective: A Prospective Study. Life (Basel). 2022;12(12): 2000. doi:10.3390/life12122000
5. Tuyết TTÁ, Thịnh NTTT, Tùng NL, Bình NC, Kỳ TD, Quang NNM. Đánh giá kết quả điều trị viêm đường mật cấp do sỏi ống mật chủ ở bệnh nhân cắt dạ dày theo Billroth II bằng nội soi mật tụy ngược dòng. Journal of 108 - Clinical Medicine and Phamarcy. Published online December 1, 2022. doi:10.52389/ydls.v17i7.1547
6. Chandrasekhara V, Khashab MA, Muthusamy VR, et al. Adverse events associated with ERCP. Gastrointestinal Endoscopy. 2017;85(1):32-47. doi:10.1016/j.gie.2016.06.051
7. Gellért B, Patai ÁV, Hritz I. Update in preventing post-endoscopic retrograde cholangiopancreatography pancreatitis. Ann Gastroenterol. 2024;37(3): 266-279. doi:10. 20524/aog.2024.0870
8. Đông ND, Hai NV, Phú LV, Quân ĐH, Chường NH. Kết quả sớm điều trị sỏi đường mật chính bằng phương pháp nội soi mật tụy ngược dòng tại Cần Thơ. ctump. 2024;(77):92-98. doi:10.58490/ ctump.2024i77.2798