ĐÁNH GIÁ KẾT QUẢ BƯỚC ĐẦU XẠ TRỊ IGRT TRONG ĐIỀU TRỊ UNG THƯ PHỔI KHÔNG TẾ BÀO NHỎ TẠI BỆNH VIỆN K

Abstract

Lung cancer is the most common cancer in Viet Nam. Concurrent chemoradiation therapy for lung cancer stage IIB - III which is not surgery and refused. IMRT followed by IGRT is a modern technique that utilizes multileaf collimator system to optimize radiation plan with increasing homogeneity of target therapy, minimizing the dose to organ at risks and radiation is accurate to PTV. Our study aims to review the results and early side effects of concurrent chemoradiation therapy by IMRT and followed IGRT for treatment of non-small cell lung cancer stage IIB - III at K hospital. Methods: 30 patients with lung cancer at stage IIB - III who are treated by concurrent chemoradiation therapy without surgery at K Hospital, using EP 2cycles and 60Gy of RT; using IMRT follow by IGRT technique. IGRT can evaluate to move of tumor and organs at rist in radiation therapy lung cancer; Evaluation of adverse effects every 10Gy of treatment and respond at the end of concurrent chemoradiation therapy. Result: Treatment plan of IMRT followed by IGRT help to radiation therapy is accurate and forcus on PTV. On the other hand, the moving of tumor must be followed cartesian coordinate system < 0.3cm, the diaphragm is maximum of moving: 1.24±0.62 cm in comparison with other organs inside chest. PR of tumor: 86.7%, CR of lymph nodes up to: 60.8%. Rate of pneumonia early complication grade 3: 3.3%. Esophagitis early complication grade 6.7%. Conclusion: In our study, we found that use IMRT followed by IGRT technique, we realize that moving of the tumor get accept of limit, radiation therapy focusing the dose on PTV, make to increase the result of risponse and the side effects of IMRT followed by IGRT group were lower.