IMAGING CHARACTERISTICS OF POSITIVE SCREENING LUNG NODLES WITH LUNG-RADS BY LOW-DOSE COMPUTED TOMOGRAPHY
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Abstract
Objective: Describe the imaging characteristics of positive creening lung nodules with Lung-RADS by low-dose computed tomography (LDCT). Subjects and methods: A cross-sectional prospective study was conducted on all patients who underwent LCT and had positive lung nodule screening results with Lung-RADS at Hanoi Medical University Hospital from January 2024 to December 2024. Results: There were 96 cases that suitbale with the selection criteria with lung nodules classified as Lung-RADS 3, 4A, 4B and 4X. The medium age was 56 ± 12 years old, the age group from 50 to 80 years old was the highest (59.4%). Male patients accounted for 79.2% of the study subjects. 46.9% of patients had smoking habits at different levels. There were 48 patients (45.8%) had lung nodules classified as Lung-RADS 4A, 4B and 4X with a high risk of malignancy. Lung-RADS was statistical significantly to the age and smoking habits of the patients. LDCT detected 14 cases of lung cancer in 96 cases of positive lung nodule screening (accounting for 14.6%). The radiation dose of LDCT was significantly lower at 92.4% than standard CT. Conclusion: LDCT scan has a practical role in lung nodule screening, while significantly limiting radiation risk. Lung-RADS is useful in diagnosis, management recommendations, and follow-up of lung nodules.
Article Details
Keywords
Low-dose computed tomography, lung nodule, positive screening, Lung-RADS, lung nodule, positive screening.
References
2. National Lung Screening Trial Research Team. Reduced lung-cancer mortality with low-dose computed tomographic screening. N Engl J Med. 2011;365(5): 395-409. doi:10.1056/ NEJMoa1102873
3. New England Journal of Medicine. Lung cancer screening and the NELSON trial results. New England Journal of Medicine. 2020; 382(22):2164-2166. doi:10.1056/NEJMc2004224
4. Lung-RADS-2022. Accessed June 13, 2024. https://www.acr.org/-/media/ACR/Files/RADS/ Lung-RADS/Lung-RADS-2022.pdf
5. Xiaojing Wang, Hongli Liu, Yuanbing Shen, Wei Li, Yuqing Chen, Hongtao Wang. Low-dose computed tomography (LDCT) versus other cancer screenings in early diagnosis of lung cancer: A meta-analysis. Medicine. 2018;97(27): e11233. doi:10.1097/MD.0000000000011233
6. Frederick J. Larke, Randell L. Kruger, Christopher H. Cagnon, et al. Estimated radiation dose associated with low-dose chest CT of average-size participants in the National lung screening trial. American Journal of Roentgenology. 2011;197(5): 1165-1169. doi:10. 2214/AJR.11.6533
7. US Preventive Services Task Force, Alex H. Krist, Karina W. Davidson, et al. Screening for lung cancer: US preventive services task force recommendation statement. JAMA. 2021;325(10): 962. doi:10.1001/jama.2021.1117
8. American Cancer Society. Lung cancer early detection | Lung cancer screening. Accessed July 17, 2024. https://www.cancer.org/cancer/types/ lung-cancer/detection-diagnosis-staging/ detection.html
9. Trịnh Việt Anh, Vũ Hồng Anh, Phạm Thị Thanh Loan. Đánh giá kết quả bước đầu sàng lọc phát hiện ung thư phổi ở bệnh nhân nguy cơ cao bằng chụp CLVTLT tại Bệnh viện E. Accessed March 12, 2025. https://tapchiyhocvietnam. vn/index.php/vmj/article/view/9581/8439
10. Đặng Đình Phúc, Ngô Quốc Bộ, Đinh Hoàng Việt, Nguyễn Quốc Đạt. Giá trị của phân loại Lung-RADS trong chẩn đoán ung thư phổi với nốt mờ đơn độc. Accessed March 12, 2025. https://tapchiyhocvietnam.vn/index.php/vmj/article/view/3797/3484