MỐI LIÊN QUAN GIỮA NỒNG ĐỘ GLUCOSE MÁU VỚI MỘT SỐ BIẾN CHỨNG XƠ GAN Ở BỆNH NHÂN XƠ GAN RƯỢU CÓ ĐÁI THÁO ĐƯỜNG

Abstract

Objective: To investigate the association between blood glucose levels and cirrhosis-related complications in patients with alcoholic cirrhosis and diabetes mellitus. Subjects and Methods:This was a cross-sectional descriptive study conducted on 68 patients diagnosed with alcoholic cirrhosis and diabetes mellitus from August 2024 to May 2025. Results: Among the 68 patients with alcoholic cirrhosis, 61 had a known history of diabetes mellitus, while 7 were newly diagnosed. Cirrhosis-related complications included ascites (70.6%), upper gastrointestinal bleeding due to portal hypertension (38.2%), hepatic encephalopathy (19.1%), hepatorenal syndrome (4.4%), and spontaneous bacterial peritonitis (3.0%). Regarding blood glucose levels, the prevalence of 2-hour postprandial hyperglycemia was 94.1%, and hypoglycemia was observed in 19.1% of patients. Thirteen patients experienced hypoglycemia, both symptomatic and asymptomatic, with daytime hypoglycemia being more common than nighttime episodes. Asymptomatic hypoglycemia was more frequent than symptomatic cases. The lowest recorded blood glucose level was 2.6 mmol/L. A statistically significant association was found between infectious complications and hypoglycemia (p< 0.05). Conclusion: Infectious complications increase the risk of hypoglycemia in patients with alcoholic cirrhosis and diabetes mellitus.