ENDOSCOPIC AND BIOPSY CHARACTERISTICS OF EOSINOPHILIC GASTROENTERITIS IN CHILDREN AT CHILDREN'S HOSPITAL 2

Văn Thiệu Hà, Quốc Pháp Hồ, Huy Khôi Hà, Thị Thu Thuỷ Nguyễn, Văn Bách Ngô, Ngọc Hân Võ

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Abstract

Objective: To describe the endoscopic and biopsy characteristics of EGE at Children's Hospital No.2 from January 2018 to August 2024. Subjects: Children diagnosed with eosinophilic gastroenteritis at Children's Hospital 2. Research Method: Case series descriptive study. Results: 100% of patients underwent gastroscopy and duodenoscopy, 88% underwent colonoscopy. 40% of patients have a history of allergies. The time from symptom onset to diagnosis was 1-6 months in 56% of cases. The severity of peripheral eosinophilia (mild, moderate, and severe) was 35%, 35%, and 30% respectively. On abdominal CT scans, common findings include ascites (80%) and bowel wall thickening (70%). - Most patients had biopsies taken from more than one site. The percentage of patients who underwent biopsy via gastrointestinal endoscopy combined with exploratory laparotomy and those who only had a gastrointestinal endoscopy biopsy were 52% and 48%, respectively. - There was no significant difference between the number of eosinophils in the blood and the presence of ascites (p> 0.05). Conclusion: EGE is often diagnosed late, possibly due to its non-specific and varied symptoms, that can easily be mistaken for other gastrointestinal diseases. In clinical practice, EGE should be considered when there are persistent gastrointestinal symptoms accompanied by elevated eosinophil count, with or without ascites, and after other causes have been ruled out.

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References

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