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THE LEFT ATRIAL MORPHOLOGY AND FUNCTION BY ECHOCARDIOGRAPHY IN PATIENTS WITH END-STAGE CHRONIC KIDNEY DISEASE WITH INDICATIONS FOR KIDNEY TRANSPLANTATION
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Abstract
Objective: To investigate the changes in the left atrial morphology and function by echocardiography in patients with end-stage chronic kidney disease who are candidates for kidney transplantation. Subjects and methods: A cross-sectional descriptive study of 63 patients diagnosed with end-stage chronic kidney disease who are candidates for kidney transplantation at Military Hospital 103 from October 2024 to April 2025. Results: Left atrial diameter (LAD) 35.11 ± 6.72 mm, left atrial volume index (LAVi) 29.09 ± 13.12 ml/m², slightly increased compared to the reference value. Left atrial dilatation strain (LASr 2B: 34.40 ± 9.73%, 4B 33.59 ± 10.71%), conduit strain (LAScd - 2B: 17.99 ± 7.71%, 4B -18.49 ± 8.53%) and contraction strain (LASct- 2B: -16.40 ± 7.75%, and 4 B: -15.10 ± 7.0%) were all lower than those in the normal population. LASct-4C had a moderate inverse correlation with age (p < 0.01), but no difference was observed between the two sexes. LAD and LAVi in the conservative treatment group were significantly lower than those in the hemodialysis group (LAD: 42.1 ± 3.3 and 35.81 ± 5.98 mm, p < 0.01) (LAVi: 23.3 ± 6.2 and 26.3 ± 5.0 ml/m2). LASr, LAScd, LASct in the 2-chamber and 4-chamber view in the conservative treatment group were significantly lower than those in the hemodialysis group (p < 0.01). LAD and LAVi in the hemodialysis treatment groups were not different between those under and over 12 months. The LASr in the 2-chamber and 4-chamber view in the group hemodialysis than 12 months (4B: 35.60 ± 9.23%, 2B: 30.91 ± 7.45%) was significantly higher than that in the group with hemodialysis under 12 months (4B: 31.86 ± 12.29%, 27.40 ± 9.70%) (p < 0.05). Conclusion: In end-stage chronic kidney disease, LAD, LAVi was slightly increased and left atrial function (LASr, LAScd, LASct) was lower in both the 2-chamber and 4-chamber views than in the normal population. LASct had a moderate inverse correlation with age (p < 0.01) but no difference was observed between the 2 sexes. Left atrial size and function were associated with pretransplant treatment, as well as with the duration of dialysis before kidney transplantation.
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Keywords
left atrial morphology, left atrial function, end-stage chronic kidney disease
References
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