THE CLINICAL FEATURES AND SURGICAL RESULTS OF ERODED GASTRIC CANCER PERFORATION

Nguyên Hưng Thái, Đình Bình Viên

Main Article Content

Abstract

Aim of study: 1. Evaluation the clinical and paraclinical features of eroded gastric cancer perforation. 2. The surgical results of eroded gastric cancer perforation. Patients and methode: Retrospective study. Results: There were 25 patients, male 72%, female 18%; average age 64,6 years (range 48-85). Epigastric pain 96,0%, melena 45,8%, gastric outlet obstruction 41,6%. Eroded gastric cancer perforation (EGCP) located at lower third  of stomach in 72,0%, middle third in  12%, upper third  in 16%. The ajacent organs to be eroded were: Head of pancreas in 44,0%; D1-D2 portion of duodenum in 52%, hepato-duodenal ligaments and hepatic segments in 36,0%; Body of pancreas 32,0%; Mesentery  of  transversal  colon 32,0%. The average diameter of  EGCP 3,14 cm (0,5-6 cm); The average diameter of gastric tumor 6,8 cm (4-10cm). Surgical procedure: Curative gastrectomy and D2 lymph node dissection in 92,0%; Palliative gastrectomy in 8,0% (peritoneal metastasis), Duodenostomy for compression in 9 patients; Plastic surgery by round ligaments to stump of duodenum (duodenal stump  located  ajacent to ampulla  of Vater). No death intra and post operation. Complication (12%): 2 patients had stumpt leakage that healing by drainage under ultrasound. 1 patient had bleeding  post operation that had re operated. Histo pathology: Stage III (b-c) 80%; Stage IV  8,0%; Gastric lymphoma tumor 8,0%; Inflammatory myo fibroblastic tumor 4,0%. Conclusion: We concluded that: The average age of eroded  gastric cancer perforation was more than 60 years (this study was 64,6 Y), predominant in male (72,0%). The symptoms were epigastric pain associated with melena and gastric outlet obstruction. EGCP located  in lower third of stomach was elevated (72%  in  this study). The average diameter of gastric cancer hole was larger  than  free perforation (3,14 cm in this study) and the average gastric tumor diameter was  larger than that of  free perforation  (6,8 cm in this study). Curative gastrectomy with D2 Lymph node dissection was performed in 92,0% and palliative gastrectomy in 8% (in this study).  Duodenostomy was performed in 9 patients  whose the duodenal stump located ajacent to ampulla of Vater.  Plastic round ligament   to duodenal stump in case  of fragile duodenal wall and duodenal stump located ajacent to the ampulla of Vate  was performed in 5 patients.  No death per and post operation.  Complication in 12%. (Duodenal stump fistula in 2 patients who were  drained under ultrasound. One patient  bleeding post operation that had re operated). Histopathology: Stage III b-c in 80,0%, stage IV in 8,0%; Gastric lymphoma  tumor 8,0%; Inflammatory myo fibroblastic tumor 4,0%  in our study.

Article Details

References

Hata T, Sakata N, Kudohk, Shibata C, Uno M. The best surgical approach for perforated gastric cancer: one stage vs two stage gastrectomy. Gastriccancer: 2014; 17 (3): 578-87.
2. Hironori Tsujimoto et al. Outcome after emergency surgery in patients with a free perforation caused by gastric cancer. Experimental and therapeutic medicine 1 199-203, 2010.
3. Nebojsa Ignjatovic, Dragan Stojanov, Miodrag Djordjevic, Jelena Ignjatovic, Daniela Benedeto Stojanov and Babana Milojkovic. Perforgation of gastriccancer - What should the surgeon do?. Bosn J Basic Med Sci, 2016 Aug;16 (3): 222-226.
4. Sara Di Carlo, Marzia Franceschilli, Piero Cavallaro, Maurizio Cardi, Danilo vinci and Simone Sibio. Perforated gastric cancer: A critical appraisal. Discov Oncol, 2021: 12:15.
5. Adachi et al. Surgical result of perforated gastric cancer: An analysis of 155 japaness patients. Am J gastroenterol.1997: 92 (3): 516-8)
6. Jungling Zang et al. Short and Long term outcomes of one stage versus two stage gastrectomy for perforated gastric cancer: a multicenter retrospective propensity score-matched study. World Journal of Surgical Oncology (2024) 22:7.
7. Naffouje SA, Salti GI. Extensive Lymph Node Dissection Improves Survival among American Patients with Gastric Adenocarcinoma Treated Surgically. Analysis of the National Center Datasebase. JGC 2017; 17(4):319-30.
8. Thái Nguyên Hưng. Điều trị phẫu thuật xuất huyết tiêu hóa nặng, sốc mất máu do loét mặt sau gối trên-DII tá tràng ở người bệnh đang điều trị bệnh lý ung thư. Tạp chí Ngoại khoa và Phẫu thuật Nội Soi Việt Nam (2024) Số 1 tập 14; 79-87.
9. Thái Nguyên Hưng, Viên Đình Bình, Trịnh Thành Vinh. Thái độ xử trí và kết quả điều tri phẫu thuật ung thư dạ dày thủng. Y học Viêt Nam tâp 551-Tháng 6-số 1-2025: 65-70