TREATMENT OUTCOMES OF CONGENITAL GASTROSCHISIS AT THE VIETNAM NATIONAL CHILDREN’S HOSPITAL
Main Article Content
Abstract
Objective: To evaluate the treatment outcomes of neonates with gastroschisis at the Vietnam National Children’s Hospital during 2018–2023, and to analyze clinical characteristics, surgical interventions, and prognostic factors. Methods: A retrospective descriptive study was conducted on 62 neonates (0–28 days old) diagnosed with and surgically treated for gastroschisis at the Vietnam National Children’s Hospital between January 2018 and December 2023. Data were collected from medical records and analyzed using SPSS 20.0, employing descriptive and comparative statistics, with p < 0.05 considered statistically significant. Results: The mean gestational age was 36.18 ± 2.53 weeks, and the mean birth weight was 2,305 ± 588.3g; 69.4% were diagnosed prenatally. The main treatment method was staged closure with silo placement (87.1%). The mean time from birth to silo placement was 7.05 ± 5.45 hours, and the mean silo duration was 8.85 ± 4.94 days. The survival rate was 71%, while mortality was 29%, primarily due to septic shock (38.9%) and respiratory failure (33.3%). Common complications included sepsis (21%), silo dislodgement (4.8%), and pneumothorax (6.5%). Conclusion: Treatment outcomes for gastroschisis have improved with early intervention, adoption of staged abdominal closure, and optimized neonatal resuscitation. Prenatal diagnosis, timely transport, effective complication management, and early postoperative enteral feeding play key roles in improving survival rates.
Article Details
Keywords
gastroschisis, silo, neonate, surgery, neonatal resuscitation.
References
2. Rentea RM, Gupta V. Gastroschisis. In: StatPearls. StatPearls Publishing; 2024. Accessed April 7, 2024. http://www.ncbi.nlm.nih.gov/ books/NBK557894/
3. Muniz VM, Lima Netto. Influence of birthplace on gastroschisis outcomes in a state in the southeastern region of Brazil. Jornal de Pediatria. 2021;97(6):670-675. doi:10.1016/j.jped.2021.02.004
4. Obeida A, El-Hussein R, NasrEldin HM, et al. Assessment of transfer-time and time-to-surgery as risk factors to survival in Gastroschisis (GS) in a LMIC; an eight-year review. Pediatr Surg Int. 2024;40(1):295.doi:10.1007/s00383-024-05872-0
5. Lee R, Dassios et al. Predictors of outcomes in infants with gastroschisis treated with a preformed silo. Pediatr Surg Int. 2024;41(1):22. doi:10.1007/s00383-024-05922-7
6. Oyinloye, et al. Challenges and Outcome of Management of Gastroschisis at a Tertiary Institution in North-Eastern Nigeria. Front Surg. 2020;7. doi:10.3389/fsurg.2020.00008
7. Okoro PE, Ngaikedi C. Outcome of management of gastroschisis: comparison of improvised surgical silo and extended right hemicolectomy. Annals of Pediatric Surgery. 2020; 16(1):5. doi:10.1186/s43159-019-0012-x
8. Räsänen L, Lilja HE. Outcome and management in neonates with gastroschisis in the third millennium—a single-centre observational study. Eur J Pediatr. 2022;181(6): 2291-2298. doi:10. 1007/s00431-022-04416-9
9. Đinh Quang Lê Thanh. Đánh giá kết quả ngắn hạn của điều trị phấu thuật hở thành bụng bẩm sinh ở trẻ sơ sinh,.2018.
10. Nguyễn Văn Linh, Nguyễn Thanh Liêm, Bùi Đức Hậu. Đánh giá kết quả bước đầu điều trị khe hở thành bụng bằng túi SILO tại Bệnh viện Nhi Trung Ương. Nghiên cứu Y học Tp Hồ Chí Minh. Published online 2011.