THE STUDY OF MULTI-SLICE COMPUTED TOMOGRALY (MSCT) IN EVALUATING THE BLOOD VESSELS OF HEPATOCELLULAR CARCINOMA

Văn Hoàng Đinh, Trường Giang Nguyễn, Văn Sang Nguyễn, Việt Hà Phạm

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Abstract

The purpose is to assess the value of multi-slice computed tomography (MSCT) in evaluating the blood vessels of hepatocellular carcinoma (HCC) prior to chemoembolization (TACE) at Thai Nguyên Central Hospital, and to compare the results with digital subtraction angiography (DSA). The methodology: A cross-sectional descriptive study was conducted, including retrospective and prospective data collection from 51 HCC patients who underwent TACE at Thai Nguyên Central Hospital from January 2023 to June 2025. All patients had pre-procedure MSCT imaging, and data analysis was performed using SPSS 25.0 software. Results: The average age was 61.8 ± 12.1 years, with most patients over 50 years old. The male-to-female ratio is 9.2/1. The average tumor size was 7.6 ± 3.6 cm, ranging from 1.9 to 16 cm. The tumors most commonly located in the right liver lobe (90.2%). The most common anatomical variation of the hepatic artery is Type I (according to Michel). The main blood supply to the tumor originated from the right hepatic artery (78.4%). Eleven patients (21.6%) had extra-hepatic blood supply, the right inferior phrenic artery (81.8%), the left inferior phrenic artery and the gastroduodenal-mesocolic artery (9.1%). The accuracy of MSCT in detecting the extra-hepatic blood vessels supplying the tumor was 90.9% sensitivity, 95% specificity, and 94% overall accuracy. Conclusion: Multi-slice CT imaging is highly valuable in assessing the blood vessels in HCC, especially in visualizing extra-hepatic blood supply. Comprehensive pre-intervention imaging is essential to optimize techniques and improve treatment outcomes.

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References

1. Bộ Y tế. Hướng dẫn chẩn đoán và điều trị ung thư biểu mô tế bào gan. (2020).
2. Bray, F. et al. Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 74, 229-263, doi:10.3322/caac. 21834 (2024).
3. Doãn Văn Ngọc, H. Đ. Â. Đặc điểm hình ảnh và vai trò của cắt lớp vi tính trong chẩn đoán ung thư biểu mô tế bào gan. Tạp chí Y học Việt Nam 524 (2023).
4. Nguyễn Văn Nam, N. P. B. Q., Huỳnh Minh Phú,. Nghiên cứu đặc điểm hình ảnh và giá trị của hình ảnh cắt lớp vi tính trong chẩn đoán ung thư biểu mô tế bào gan tại bệnh viện ung bướu thành phố Cần Thơ năm 2021-2023. Tạp chí Y Dược học Cần Thơ, 1-8 (2023).
5. Abou Khadrah, R. S., Abedelmalik, M. H., Alameldeen, M. A. E. & Elbarbary, A. A. Hepatocellular carcinoma vascularization: CT angiography variations identifying arteries feeding the tumour. Egyptian Journal of Radiology and Nuclear Medicine 54, 183, doi:10.1186/s43055-023-01133-7 (2023).
6. Kim, H. C., Chung, J. W., Lee, W., Jae, H. J. & Park, J. H. Recognizing extrahepatic collateral vessels that supply hepatocellular carcinoma to avoid complications of transcatheter arterial chemoembolization. Radiographics 25 Suppl 1, S25-39, doi:10.1148/rg.25si055508 (2005).
7. Miyayama, S. et al. Extrahepatic blood supply to hepatocellular carcinoma: angiographic demonstration and transcatheter arterial chemoembolization. Cardiovasc Intervent Radiol 29, 39-48, doi:10.1007/ s00270-004-0287-y (2006).
8. Huyền Tôn Nữ Hồng Hạnh. Giá trị của cắt lớp vi tính trong đánh giá mạch máu của ung thư biểu mô tế bào gan có chỉ định nút mạch hóa chất. Journal of Clinical Medicine- Hue Central Hospital, doi:10.38103/jcmhch.2021.73.8 (2021).