INFLUENCING FACTORS OF SUDDEN SENSORINEURAL HEARING LOSS TREATMENT OUTCOME

Quang Lê, Lê Đình Phú Trần, Thành Phương Nguyễn

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Abstract

TREATMENT OUTCOME


Background: Sudden sensorineural hearing loss (SSNHL) is a common otologic emergency in which corticosteroids remain the mainstay of treatment. Several factors may influence treatment outcomes; however, limited data are available from Vietnam. Objective: To identify prognostic factors associated with treatment outcomes in patients with SSNHL. Methods: A prospective cross-sectional study was conducted on 162 patients diagnosed with SSNHL at Ho Chi Minh City Ear – Nose – Throat Hospital between February and September 2025. Clinical characteristics, pure tone audiometry, and treatment outcomes were collected and analyzed. Logistic regression models were applied to determine prognostic factors for hearing recovery. Results: The mean age of participants was 45,0 ± 12,7 years, and the average duration of pre-hospital delay was 8,5 ± 6,5 days. Treatment outcomes showed complete recovery in 16,0%, partial recovery in 27,8%, and no improvement in 56,2% of patients. Multivariate logistic regression revealed that older age (OR = 0,96; 95% CI: 0,94 – 0,99; p = 0,005), longer delay before treatment initiation (OR = 0,88; 95% CI: 0,82 – 0,94; p < 0,001) and baseline hearing thresholds (OR = 0,97; 95% CI: 0,97 – 0.99) were significant negative predictors of hearing recovery. Comorbidities and audiogram configurations were not significantly associated with recovery. Conclusion: Age, treatment delay, and baseline hearing threshold are independent prognostic factors for SSNHL recovery. Prompt intervention is essential to optimize treatment outcomes.

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References

1. Lương Xuân Tuyến, Nguyễn Thị Hải Hà. Kết quả bước đầu điều trị bệnh nhân bị điếc đột ngột bằng oxy cao áp tại viện y học biển. Tạp chí Y học Việt Nam. 2021.
2. Vũ Thị Ly, Thanh HC, Trọng NT, Thực ĐH, Hà ĐTT. Đặc điểm lâm sàng và yếu tố tiên lượng ở bệnh nhân điếc đột ngột. J 108 - Clin Med Phamarcy. 2021;16(DB4). doi:10.52389/ydls. v16iDB4.935
3. Chandrasekhar SS, Tsai Do BS, Schwartz SR, et al. Clinical Practice Guideline: Sudden Hearing Loss (Update). Otolaryngol Neck Surg. 2019;161(1_suppl): S1-S45. doi:10.1177/ 0194599819859885
4. Ha YR, Kim D, Kim SS, Lee JM, Kim SH, Yeo SG. Comparison of Recovery Rates of Sudden Sensorineural Hearing Loss by Age Group. J Clin Med. 2024;13(16): 4937. doi:10.3390/ jcm13164937
5. Lin W, Xiong G, Yan K, et al. Clinical Features and Influencing Factors for the Prognosis of Patients With Sudden Deafness. Front Neurol. 2022;13:905069. doi:10.3389/fneur.2022.905069
6. Lionello M, Staffieri C, Breda S, et al. Uni- and multivariate models for investigating potential prognostic factors in idiopathic sudden sensorineural hearing loss. Eur Arch Otorhinolaryngol. 2015;272(8):1899-1906. doi:10. 1007/s00405-014-2992-8
7. Mandavia R, Joshi N, Hannink G, et al. A Prognostic Model to Predict Hearing Recovery in Patients With Idiopathic Sudden Onset Sensorineural Hearing Loss. JAMA Otolaryngol Neck Surg. 2024;150(10):896-906. doi:10.1001/ jamaoto.2024.2598
8. Perez Ferreira Neto A, Da Costa Monsanto R, Dore Saint Jean L, Sonzzini Ribeiro De Souza L, De Oliveira Penido N. Clinical Profile of Patients With Unilateral Sudden Sensorineural Hearing Loss: Correlation With Hearing Prognosis. Otolaryngol Neck Surg. 2021;165(4):563-570. doi:10.1177/0194599820986571
9. Tsuzuki N, Wasano K, Oishi N. Association between atherosclerosis, hearing recovery, and hearing in the healthy ear in idiopathic sudden sensorineural hearing loss: a retrospective chart analysis. Sci Rep Dec. 2022;12(1). doi:10.1038/ s41598-022-25593-5